DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rtnl2 and Rtn3

DIOPT Version :9

Sequence 1:	NP_001246964.1	Gene:	Rtnl2 / 40903	FlyBaseID:	FBgn0015831	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	XP_006230711.1	Gene:	Rtn3 / 140945	RGDID:	620988	Length:	959	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	66/190 - (34%)
Similarity:	99/190 - (52%)	Gaps:	16/190 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NLLLWRNSRKTLIVFTGILLLLLDVMVHSVISVISMVGITVLIAAIGHRL---LVQFWSIWKKDE 82
            :|:.||:.:||..||...|::||.:...|||||:|.:.:.:|...|..|:   ::|  ::.|.:|
  Rat   773 DLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRVYKSVIQ--AVQKSEE 835

  Fly    83 NKDQILRFYPHPKIEIPREETLYLAGKAVSHINLILNRMIELLLVEKWEDSLKFLVLLCGINLLG 147
            ...  .:.|....|.:..|........|:.|:|..|..:|.|.|||...||||..|.:..:..:|
  Rat   836 GHP--FKAYLDVDITLSSEAFHSYMNAAMVHVNKALKLIIRLFLVEDLVDSLKLAVFMWLMTYVG 898

  Fly   148 DCFNGLTLLIFGHLFIFTVPKLYESYKPFVD--VQIRKFRKCKIDKSNVEKPICIQKECP 205
            ..|||:||||...|.:|:||.:||.||..:|  |.|.:.:    .||.|||   ||.:.|
  Rat   899 AVFNGITLLILAELLVFSVPIVYEKYKTQIDHYVGIARDQ----TKSIVEK---IQAKLP 951

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl2	NP_001246964.1	Reticulon	21..183	CDD:280592	58/166 (35%)
Rtn3	XP_006230711.1	Reticulon	771..935	CDD:280592	57/165 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351058
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740