DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rtnl2 and Rtn1

DIOPT Version :9

Sequence 1:	NP_001246964.1	Gene:	Rtnl2 / 40903	FlyBaseID:	FBgn0015831	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_703187.2	Gene:	Rtn1 / 104001	MGIID:	1933947	Length:	780	Species:	Mus musculus

Alignment Length:	161	Identity:	53/161 - (32%)
Similarity:	87/161 - (54%)	Gaps:	7/161 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NLLLWRNSRKTLIVFTGILLLLLDVMVHSVISVISMVGITVLIAAIGHRL---LVQFWSIWKKDE 82
            :||.||:.::|.|||...||||..:...||:||::.:.:..|.|.|..|:   ::|  ::.|.||
Mouse   595 DLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQ--AVQKTDE 657

  Fly    83 NKDQILRFYPHPKIEIPREETLYLAGKAVSHINLILNRMIELLLVEKWEDSLKFLVLLCGINLLG 147
            ...  .:.|...:|.:.:|:..........::|..|..:..|.||:...|||||.||:..:..:|
Mouse   658 GHP--FKAYLELEITLSQEQIQKYTDCLQLYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVG 720

  Fly   148 DCFNGLTLLIFGHLFIFTVPKLYESYKPFVD 178
            ..|||||||:...:.:||:|.:|..::..||
Mouse   721 ALFNGLTLLLMAVVSMFTLPVVYVKHQAQVD 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl2	NP_001246964.1	Reticulon	21..183	CDD:280592	53/161 (33%)
Rtn1	NP_703187.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..78
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..176
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..223
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..576
		Reticulon	595..757	CDD:280592	53/161 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847507
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.700