Protein Alignment Rtnl2 and RTN3

DIOPT Version :9

• Sequence 1: NP_001246964.1
• Gene: Rtnl2 / 40903
• FlyBaseID: FBgn0015831
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: XP_011543032.1
• Gene: RTN3 / 10313
• HGNCID: 10469
• Length: 1037
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 61/179 - (34%)
• Similarity: 94/179 - (52%)
• Gaps: 9/179 - (5%)

  Fly     1 MSTDTLIKAKDSSQIFMD--LKNLLLWRNSRKTLIVFTGILLLLLDVMVHSVISVISMVGITVLI 63
            :|...|:|....:::..|  :.:|:.||:.:||..||...|::||.:...|||||:|.:.:.:|.
Human   824 LSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLS 888

  Fly    64 AAIGHRL---LVQFWSIWKKDENKDQILRFYPHPKIEIPREETLYLAGKAVSHINLILNRMIELL 125
            ..|..|:   ::|  ::.|.:|...  .:.|....|.:..|........|:.|||..|..:|.|.
Human   889 VTISFRIYKSVIQ--AVQKSEEGHP--FKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLF 949

  Fly   126 LVEKWEDSLKFLVLLCGINLLGDCFNGLTLLIFGHLFIFTVPKLYESYK 174
            |||...||||..|.:..:..:|..|||:||||...|.||:||.:||.||
Human   950 LVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYK 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl2	NP_001246964.1	Reticulon	21..183	CDD:280592	57/157 (36%)
RTN3	XP_011543032.1	Reticulon	844..999	CDD:280592	57/159 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157098
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.700