Protein Alignment alpha-Est6 and Ces1a

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 170/587 - (28%)
• Similarity: 249/587 - (42%)
• Gaps: 128/587 - (21%)

  Fly    42 VVKLSVGSVKGRRLS--GIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWN------------- 91
            ||....|.|.|:.:|  | :......|.|:||||||||..||...|.|:.|:
  Rat    25 VVDTLQGKVLGKYISLEG-FTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCS 88

  Fly    92 ---------SELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAF 147
                     ||:...|...:||:.         ||||||||:|:.....|:..|||||:::||..
  Rat    89 QITGVGPVLSEVFTNQLENVPLEY---------SEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGL 144

  Fly   148 RTGGAVKSKYGPDYLMSRD-VVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHI 211
            .:|||  |.:....|.:.: ||.|:..|||...||||  :|.....||.|..||:.|||||..:|
  Rat   145 LSGGA--STFDGLALSTHEKVVVVVIQYRLGIWGFLS--TGDEHSRGNWGHFDQVAALQWVQNNI 205

  Fly   212 RNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATS 276
            .||.|||.::||||||||..||..::..|..|.|||:||..||..|:|.:...::     |||
  Rat   206 VNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNLFHRAISESGVALTPCLFRENT-----RLA-- 263

  Fly   277 AGYEGPAEEV------------PILEFLRNVNAEKLIG------------HDFISPRDRCFGFLN 317
                  ||:|            .|:..||....|:|:.            |.  .||: .:.||
  Rat   264 ------AEQVAIATGCAATTSADIVRCLREKTEEELLATTLKMKFFALDLHG--DPRE-SYPFL- 318

  Fly   318 PFAPVVGG--LVAAPFQQLMKEAWSCEVPLLLG------GTSFEGLVYYPFCQ--LDNGYMLELL 372
              ..|:.|  |..|| ::::.|.....||.::|      |.....::.||..:  ||......||
  Rat   319 --TTVIDGVLLPKAP-EEILSEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLL 380

  Fly   373 -KHEPAMVLPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVL 436
             |..|...:..||            ..|..:.:.|............||:....||  .:..|::
  Rat   381 WKSYPLTNISKEL------------TPVATEKYLGGSDCPDKKKDLFLDMMGDVLF--AVPSVIV 431

  Fly   437 SRLSH-AQAPTYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDL----GYIFHKQAQAKQPLDS 496
            :|... |:|.||:|.|.:....::.||.:....|      |.|::    |..|.|:..:::.::.
  Rat   432 ARYHRDARATTYVYEFKYHPSFVSDMRPKTVIAD------HGDEVYSVWGTPFLKEGASEEEINL 490

  Fly   497 PEFLTIQRMVGILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWN 561
            ...     |:.....|||.|:||  ..|...|.....|..:  |.||..::...:::...:..|.
  Rat   491 STM-----MMKFWGNFARNGNPN--GEGLPHWPEYDEKESY--LQIGTTIQQAQKLKYKEVAFWT 546

  Fly   562 RL 563
            .|
  Rat   547 GL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	165/558 (30%)
Ces1a	NP_001177304.1	COesterase	22..545	CDD:395084	168/582 (29%)