Protein Alignment alpha-Est6 and Ces5a

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 563
• Identity: 156/563 - (27%)
• Similarity: 240/563 - (42%)
• Gaps: 124/563 - (22%)

  Fly    47 VGSVKGRRLSGIYG--DEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQ---- 105
            :|.|:|::.: :.|  :....|.|||||.||||..||...|...||::..:|.....:..|
Mouse    41 LGWVQGKQAT-VLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNLEW 104

  Fly   106 ------MDRRSGKVVG-SEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKY-GPDYL 162
                  :.:.|..::| ||||||||:|......:...|||||:|.||.|.||.|  |.: |....
Mouse   105 LFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSA--SIFDGSALA 167

  Fly   163 MSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGES 227
            :..||:.|...|||...||.:  :.....|||....|||.||.||.::|:.|.|:|.::|:||.|
Mouse   168 VYEDVLVVTIQYRLGIFGFFT--TQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNS 230

  Fly   228 AGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSD----------GIFCRLATSAGYEGP 282
            |||.|:..::..|.:..|||:|||.||..:.|.:.:.|:|          ...|.::.|..
Mouse   231 AGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVVANVCDCNVSDSKA---- 291

  Fly   283 AEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGG--LVAAPFQQLMKEAWSCEVPL 345
                 :|:.||..::.:|:.   :|.:.:      .|..||.|  ....|.:.|.::.... ||.
Mouse   292 -----LLKCLREKSSLELMS---LSQKAK------SFTRVVDGSFFSEEPLELLSQKTLKI-VPS 341

  Fly   346 LLGGTSFEGLVYYPFCQLDNGYML------ELL---KHEPAMVLPHELY----QSMSVEERNTAA 397
            ::|..:.|       |    ||:|      |:|   ....|:.|.|.|.    |.:.:
Mouse   342 IIGVNNQE-------C----GYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYI------- 388

  Fly   398 DVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSH-AQAPTYLYRFDFDSPKLNLM 461
             |..:|.:|....|....| :||||....|  .:..:|.:|... :..|.|.|.|..........
Mouse   389 -VTKEYFHGKHSPTDIRDT-LLDLFGDVFF--VVPGLVTARYHRDSGGPVYFYEFQHRPHCFQNS 449

  Fly   462 RNQLCGDDIKRGVCHADDLGYIF-----------HKQAQAKQPLDSPEFLTIQRMVGILTTFART 515
            |......|      |.|::.::|           .::|..::.|.|      ::|:.....|||:
Mouse   450 RPAFVKAD------HTDEIRFVFGGPFLKGDVVMFEEATEEEKLLS------RKMMKYWANFARS 502

  Fly   516 GDPNCPETGPD--PWMPVSTKSPFKALNIG---------QQVE 547
            ||||    |.|  ||........:..|::.         |:||
Mouse   503 GDPN----GADLPPWPVYDENEQYLELDVNISTGRRLKDQRVE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	152/539 (28%)
		Aes	<133..325	CDD:223730	66/202 (33%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	156/563 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840