Protein Alignment alpha-Est6 and Ces2b

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001094469.1
• Gene: Ces2b / 679149
• RGDID: 1591847
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 155/546 - (28%)
• Similarity: 230/546 - (42%)
• Gaps: 120/546 - (21%)

  Fly    40 SKVVKLSVGSVKGR------RLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQ 98
            |.:....:|.|:|:      ..:|:     ::|.||||||||:|..||...:..:||:...|...
  Rat    33 SPIRNTHIGQVRGKLDHVKDTKAGV-----HTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTS 92

  Fly    99 ERPIPLQ------------MDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGG 151
            :..:.||            |..:...|..||||||||:|..........|||||:|:||...||.
  Rat    93 QPAMCLQNLDVINAEGLKEMKLKLPPVSMSEDCLYLNIYAPAHAHEGSNLPVMVWIHGGGLMTGM 157

  Fly   152 AVKSKYGPDYL-MSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFN 215
            |  |.|....| ::.|:|.|...|||..|||.|  :|.....||.|..||:.||:||.|:|.:|.
  Rat   158 A--SMYDGSLLTVNEDLVVVTIQYRLGVLGFFS--TGDEHARGNWGYLDQVAALRWVQQNIAHFG 218

  Fly   216 GDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYE 280
            |:|..:|:||||||...|...:..|.::||||.|||.||..|.|::.|..|:.....:|..:|.|
  Rat   219 GNPDRVTIFGESAGGTCVSTHVVSPMSQGLFHGAIMESGVALLPYLIADTSEMFSTMVAKVSGCE 283

  Fly   281 GPAEE-----------------------VPIL---EFLRNVNAEKLIGHDFISPRDRCFGFLNPF 319
            ....|                       ||.:   |||.....|.|...||           .|.
  Rat   284 AMDSEALVHCLRAKSEAEILAINKVVQMVPAVVDGEFLPRHPKELLASEDF-----------RPV 337

  Fly   320 APVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPA-MVLPHE 383
            ..::|         :..:.:...:||::|.|..       ..:|....:..:||...| ::||.|
  Rat   338 PSIIG---------VNNDEYGWTIPLVMGTTQM-------IKELSRENLQAILKKTTAQLMLPLE 386

  Fly   384 LYQSMSVEERNTAADVLVKYHYG----PRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQA 444
                        .:|:|::.:.|    |:.: ::..|::::.|.:.     |..:.::....:.|
  Rat   387 ------------CSDLLMEEYMGDIEDPKTL-QAQFTELMEDFMFV-----IPALQVAHFQCSHA 433

  Fly   445 PTYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDL----GYIFHKQAQAKQPLDSPEFLTIQRM 505
            |.|.|.|......|..:|......|      |.|::    ||.|.   ..|......|.|..:||
  Rat   434 PVYFYEFQHQITFLKDIRPPHVKAD------HGDEIPFVFGYFFW---DMKTDFTEEEKLLSRRM 489

  Fly   506 VGILTTFARTGDPNCPETGPDPWMPV 531
            :.....|||.|:||  ..|...| ||
  Rat   490 MKYWANFARHGNPN--SEGLSYW-PV 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	155/546 (28%)
Ces2b	NP_001094469.1	COesterase	32..540	CDD:395084	155/546 (28%)