Protein Alignment alpha-Est6 and Aadac

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_065413.1
• Gene: Aadac / 57300
• RGDID: 631440
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 71/322 - (22%)
• Similarity: 108/322 - (33%)
• Gaps: 91/322 - (28%)

  Fly   122 LNVYTKHFNESEPPLPVMVY---------------IYGGAFRTGGAVKSKYGPDYLMSR-----D 166
            :.|....||.    :||.:|               |:||.:..|.|....|  |.|..|     |
  Rat    78 VTVMETDFNS----VPVRIYIPKRKSTTLRRGLFFIHGGGWCLGSAAYFMY--DTLSRRTAHRLD 136

  Fly   167 VVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQH--IRNFNGDPQNITLFGESAG 229
            .|.|..:|.|         :.|...|..  ..|...:|:|..|.  :..:..||:.:.:.|:|||
  Rat   137 AVVVSTDYGL---------APKYHFPKQ--FEDVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAG 190

  Fly   230 ----AASVHFMMCLPQAK------GLFHKAI-----------------MMSGSMLSP-WVN--AP 264
                ||....::..|..|      .|.:.|:                 :::.|:|.. |..  ..
  Rat   191 GNLTAAVTQQILQDPDVKIKLKVQALIYPALQALDMNVPSQQENSQYPLLTRSLLIRFWSEYFTT 255

  Fly   265 DSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAA 329
            |.|   ...|.......|.|...:|:|   ||...|:      |:....|:... .|..|.|..|
  Rat   256 DRD---LEKAMLLNQHVPVEFSHLLQF---VNWSSLL------PQRYKKGYFYK-TPTPGSLELA 307

  Fly   330 PFQQLMKEAWSCEVPLLLGGTSFEGL--VYYPFCQL----DNGYM-LELLKHEPAMVLPHEL 384
            .......:..:|  |||...:....|  .|...||.    |:|.| ::.|::....|..|.:
  Rat   308 QKYPGFTDVKAC--PLLANDSILHHLPMTYIITCQYDVLRDDGLMYVKRLQNTGVHVTHHHI 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	71/322 (22%)
Aadac	NP_065413.1	Abhydrolase_3	106..373	CDD:400284	65/290 (22%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		0/1 (0%)