Protein Alignment alpha-Est6 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 676
• Identity: 159/676 - (23%)
• Similarity: 256/676 - (37%)
• Gaps: 215/676 - (31%)

  Fly     2 WKL------CQPRSRSRIKCFRFLILR----------CCPGFKRFSCQSA--------------G 36
            |::      .|.|.:..:....:|.:|          ||   .|.:|..:              |
Zfish     3 WRIFSAYIGVQQRQQHPVSQTMWLAMRKKRLLLHHQDCC---SRRACNISLWILVFCWCMMLVRG 64

  Fly    37 DADSKVVKLSVGSVKGRRL---SGIYG--DEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDA 96
            ......|....|.::|.|:   |.|.|  |::.   |:|:|.||:|:.||:..:....|:...:|
Zfish    65 QGYYPTVNTQYGKLRGARVPLHSEILGPVDQYL---GVPYATPPVGEKRFLPPEPPSSWSGIKNA 126

  Fly    97 RQERPI-PLQMDRRSGKVV------------------GSEDCLYLNVYT---------------- 126
            ....|: |..:.....:::                  .:|||||||:|.
Zfish   127 THFAPVCPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKP 191

  Fly   127 ---------KHFNESEPPL-----------------PVMVYIYGGAFRTG------GAVKSKYGP 159
                     .|..:....|                 ||||||:||::..|      |:|.:.||
Zfish   192 NKKICRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG- 255

  Fly   160 DYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLF 224
                  :|:.:..|:|:..|||||  :|.....||.||.||:.||:|:|::|..|.||...||:|
Zfish   256 ------NVIVITLNFRVGVLGFLS--TGDQAAKGNYGLLDQIQALRWISENIGYFGGDSNRITVF 312

  Fly   225 GESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPD-------SDGIFCRLATSAGYEG 281
            |...||:.|..:.....::||||:||:.|||.||.| ||...       ::.:.|.:
Zfish   313 GSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNV-------- 369

  Fly   282 PAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVV-GGLVAAPFQQLMKEAWSCEVPL 345
             .:.:.:::.||..:|.:|:..|....|     :...|.||: |.::....:.||::.......:
Zfish   370 -LDTLDMVDCLRKKSARELVEQDIQPAR-----YHVAFGPVIDGDVIPDDPEILMEQGEFLNYDI 428

  Fly   346 LLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYG-PRG 409
            :||....|||.:     ::|             |:..|  ..:|..:.:.:....|...|| |.|
Zfish   429 MLGVNQGEGLRF-----VEN-------------VVDSE--DGVSGNDFDFSVSDFVDSLYGYPEG 473

  Fly   410 ITKSNITQILDLFSY-----------------KLF----WHGIHRVVLSRLSHAQ--APTYLYRF 451
              |..:.:.:. |.|                 .||    |  :...|::...||:  :|||.|.|
Zfish   474 --KDTLRETIK-FMYTDWADRDNPETRRKTLVALFTDHQW--VEPSVVTADLHARYGSPTYFYAF 533

  Fly   452 DFDSPKLNLMRNQLCGDDIK---RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGIL---- 509
                       ...|...:|   ....|.|::.|:|.........|....|.....|:..:
Zfish   534 -----------YHHCQSLMKPAWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAVVMTY 587

  Fly   510 -TTFARTGDPNCPETGPDPWMPVSTK 534
             |.||:|||||.|       :|..||
Zfish   588 WTNFAKTGDPNKP-------VPQDTK 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	149/609 (24%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	149/607 (25%)