Protein Alignment alpha-Est6 and Cesl1

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_063134329.1
• Gene: Cesl1 / 501232
• RGDID: 1565666
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 626
• Identity: 191/626 - (30%)
• Similarity: 266/626 - (42%)
• Gaps: 135/626 - (21%)

  Fly     2 WKLCQPRSRSRIKCFRFLILRCCPGFKRFSCQSAGDADS-KVVKLSVGSVKGR--RLSGIYGDEF 63
            |.:| ||.    .|.|.|.|     ....:|...|:..| .||....|.|.|:  .|.|: ....
  Rat    29 WSIC-PRK----MCLRSLFL-----VSLATCVVCGNPSSPPVVDTMKGKVLGKYASLEGV-TQSV 82

  Fly    64 YSFEGIPFAKPPLGKARFVASQLADPW-----------------------NSELDARQERPIPLQ 105
            ..|.|:||||||||..||...|.|:||                       |..|..|:|: :.||
  Rat    83 AVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDATKGQRMNDLLTNRKEK-VHLQ 146

  Fly   106 MDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMS-RDVVY 169
            .         ||||||||:||......:..:||||:|:||....|||  |.|....|.: .:||.
  Rat   147 F---------SEDCLYLNIYTPADFTKDSRMPVMVWIHGGGLTQGGA--STYDGQVLSAYENVVV 200

  Fly   170 VLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVH 234
            |...|||...||.|  :|.....||.|..||:.||.||..:|.||.|||.::|:||||||..||.
  Rat   201 VAIQYRLGIWGFFS--TGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVS 263

  Fly   235 FMMCLPQAKGLFHKAIMMSGSMLSPWVNAPD--------SDGIFCRLATSA----GYEGPAEEVP 287
            .::..|.:|.|:|:||..||.:|...:...|        :|...|:..|||    ......|| .
  Rat   264 VLVLSPLSKNLYHRAISESGVVLITELFTKDVRPAAKQIADMAGCKTTTSAIIVHCLRQKTEE-E 327

  Fly   288 ILEFLRNVNAEKLIGHDFISPRD--RCFGFLNPFAPVVGGLVAA--PFQQLMKEAWSCEVPLLLG 348
            :||.:..:|..||     .|.||  ..:.||   :.|:..:|..  | ::::.|.....||.::|
  Rat   328 LLEIMEKMNLIKL-----SSQRDTKESYHFL---STVIDDVVLPKDP-KEILAEKNFNTVPYIVG 383

  Fly   349 ------GTSFEGLVYY--PFCQLDNGYMLELL-KHEPAMVLPHELYQSMSVEERNTAADVLVKYH 404
                  |.....::.:  |..:||....:.|| |......:|.::. .:::|:....:|..:|..
  Rat   384 INKQECGWLLPTMMRFVPPDVKLDKKMAIMLLEKFASIYGIPEDII-PVAIEKYRKGSDDPIKIR 447

  Fly   405 YGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSH--AQAPTYLYRF----DFDSPKLNLMRN 463
            .|           ||......||.  |..|::|| .|  |.||||:|.:    .|.||:   ...
  Rat   448 DG-----------ILAFIGDALFC--IPSVMVSR-DHRDAGAPTYVYEYQYYPSFSSPQ---RPK 495

  Fly   464 QLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMV-GILTTFARTGDPNCPETGPDP 527
            .:.||       ||||:..:|  .|...:...|.|.:.:.:|| .....|||.|:||  ..|...
  Rat   496 DVVGD-------HADDVYSVF--GAPILRDGASEEEIKLSKMVMKFWANFARNGNPN--GRGLPH 549

  Fly   528 WMPVSTKSPFKALNIGQQVECVTQVEKDGLKV-----WNRL 563
            |.....|..:  |.||     .|..:..|||.     |.:|
  Rat   550 WPQYDQKEEY--LQIG-----ATTQQSQGLKAEEVAFWTQL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	172/555 (31%)
Cesl1	XP_063134329.1	None