Protein Alignment alpha-Est6 and Nlg4

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 176/723 - (24%)
• Similarity: 257/723 - (35%)
• Gaps: 246/723 - (34%)

  Fly    32 CQSAGDAD--------SKVVKLSVGSVKGRRLSGIY--GDEF------YSFEGIPFAKPPLGKAR 80
            |..|..||        .::|:...|     ||.|:.  .|.|      ..|.|:|:|.||..:.|
  Fly    25 CAGASTADIYKGARLGHRIVQTRYG-----RLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNR 84

  Fly    81 FVASQLADPWN--------------------SELDARQERP----------IPLQMDRRSGKVVG 115
            |..::...||:                    :|..|.::.|          :|...::
  Fly    85 FSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQ------- 142

  Fly   116 SEDCLYLNVYTK-HFNESEPPLPVMVYIYGGAFRTG------GAVKSKYGPDYLMSRDVVYVLFN 173
            |||||||||::. :...:|..|||:|:|:|.:|...      |:|.:.||       :||.|..|
  Fly   143 SEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYG-------EVVVVTLN 200

  Fly   174 YRLCSLGFLSM---PSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHF 235
            |||..||||:.   |.....| .|.||.||:.||.|:.|:|:.|.|||.::||.|...|||.:::
  Fly   201 YRLGILGFLNANPNPHAHARV-ANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINY 264

  Fly   236 MMCLP-QAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAE----EVPILEFLRNV 295
            :|..| ..:||||:||:||||..|.|....|......:||.......|.:    ...|::.||:|
  Fly   265 LMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDV 329

  Fly   296 NAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLL------------- 347
            ..|.|...|..:|     .||..|.|.|.|:|..|...      :.::..|:
  Fly   330 PLEDLYLADIQAP-----NFLTSFGPSVDGVVIRPGHS------NLDIDDLMARNSRRSSADSGF 383

  Fly   348 ---------------------GGTSFEGLVYYPFCQLDNGYM-------LELLKHEPAM------ 378
                                 .|:||.|           ||.       :.:..|...:
  Fly   384 QSSAGGGGGQGGGAGGGGGGGSGSSFGG-----------GYFGGSGAGTMNMGGHYDVLFGVVTG 437

  Fly   379 -----VLPHELYQSMSVEERNTAADVLVK--YHYGPRGITKSNITQILDLFSYKLFW-----HGI 431
                 ...|::......|.|:......|:  |:|....|..:.:.:..|       |     |.|
  Fly   438 ESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTD-------WDRTSQHPI 495

  Fly   432 HR--VVLSRLSHAQ--AP-------------------------------------------TYLY 449
            :.  ..::.||.||  ||                                           .|.|
  Fly   496 NTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFY 560

  Fly   450 RFDFDSPKLNLMRNQLCGDDIKR-GVCHADDLGYIFHKQ-----AQAKQPLDSPEFLTIQRMVGI 508
            .||:.:..         ||..:| |..|.:||.|||...     :...|.....|....:.::..
  Fly   561 VFDYQTKD---------GDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIF 616

  Fly   509 LTTFARTGDPNCPETGPDPWMPVSTK------------SPF--KALNIGQQVECVTQVEKDGLKV 559
            .|.|||||:|| .....|..:|||.:            .|.  |.|.||.:...........|.:
  Fly   617 WTNFARTGNPN-EHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSI 680

  Fly   560 WNRLYSDL 567
            |.||..:|
  Fly   681 WLRLIPEL 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	163/681 (24%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	168/696 (24%)