Protein Alignment alpha-Est6 and Ces1b

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 573
• Identity: 174/573 - (30%)
• Similarity: 252/573 - (43%)
• Gaps: 94/573 - (16%)

  Fly    40 SKVVKLSVGSVKGRRLSGIYGDE--FYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERP- 101
            |.||..:.|.:.|:..| :.|.|  ...|.|:||||||||..||...:.|:||:...:|....|
Mouse    23 SPVVDTTQGKILGKYTS-LEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPM 86

  Fly   102 -------IPLQMDRRSGK-----VVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVK 154
                   :.|..|..|.|     .:.||||||||:|:.........|||||:|:||...||||
Mouse    87 CSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGA-- 149

  Fly   155 SKYGPDYLMSRD-VVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDP 218
            |.|....|.:.: ||.|...|||...|..|  :|.....||....|||.||:||..:|.||.|:|
Mouse   150 SLYNGLALSAHENVVVVTIQYRLGIWGLFS--TGDEHSRGNWAHLDQLAALRWVQDNIANFGGNP 212

  Fly   219 QNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRL----ATSAGY 279
            .::|:||.|||..||..::..|.||.|||:||..|..:|...|...|.  :.|.|    ||.:|.
Mouse   213 DSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDL--VACDLSQMIATVSGC 275

  Fly   280 EGPAE-----------EVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLV--AAPF 331
            ...:.           |..:||....:...| :|....:.:|.     ...:.|:.|:|  .||.
Mouse   276 NDTSSTAMVQCLRQKTENELLEITVKLEVTK-VGGAASAKKDN-----TSMSTVIDGVVLPKAPE 334

  Fly   332 QQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYML-----ELL-----KHEPAMVLPHELYQ 386
            :.|.::::| .||.::|           |.:.:.|:::     :||     ..|.|.:|....:.
Mouse   335 EILAEKSFS-TVPYIVG-----------FNKQEFGWIIPTMLGDLLSEGKMNEETASLLLRRFHS 387

  Fly   387 SMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSR-LSHAQAPTYLYR 450
            .:::.|....| |:.||..|.....|.. ..:||:||...|  ||..|:||| |..|...||:|.
Mouse   388 DLNISESLIPA-VIEKYLRGTDDPAKKR-DLLLDMFSDVFF--GIPAVLLSRSLRDAGVSTYMYE 448

  Fly   451 FDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPL----DSPEFLTIQRMV-GILT 510
            |.:....::..|.|....|      |.|::..:|      ..||    .|.|...:.:|| ....
Mouse   449 FRYRPSFVSDKRPQTVEGD------HGDEIFSVF------GIPLLKEGTSEEETNLSKMVMKFWA 501

  Fly   511 TFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRL 563
            .|||.|:||  ..|...|.....|..:  |.||...:...:::.:.:..|..|
Mouse   502 NFARNGNPN--GEGLPHWPEYDEKEGY--LQIGATTQQAQRLKAEEVAFWTEL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	168/542 (31%)
		Aes	<133..325	CDD:223730	70/207 (34%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	172/568 (30%)
		Aes	<121..>239	CDD:223730	50/121 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750