Protein Alignment alpha-Est6 and Aadacl4fm1

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_941064.2
• Gene: Aadacl4fm1 / 381572
• MGIID: 2685880
• Length: 407
• Species: Mus musculus
• Alignment Length: 242
• Identity: 53/242 - (21%)
• Similarity: 85/242 - (35%)
• Gaps: 85/242 - (35%)

  Fly   132 SEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSR--DVVYVLFNYRLCSLGFLSMPSGKLDVPGN 194
            |:|...::.:..|||..  |::.|.:.....::|  |.|.|...||  .|.:...||...|.. |
Mouse   109 SKPRRGILFFHGGGAMI--GSLDSHHNLCTFLARETDSVLVSVGYR--KLPYYHHPSLYHDCI-N 168

  Fly   195 AGLHDQLLALQWVSQHIRNFNGDPQNITLFGES-AGAASVHFMMCL------PQAKG-------- 244
            |.:|        ..:.::.:..||..:.:.||| .|||:|.....|      |:.:.
Mouse   169 ASIH--------FLKSLKAYGIDPSRVVICGESIGGAAAVVVTQTLLSRTDIPKIRAQVLIYPIL 225

  Fly   245 ----------LFHKAI-------------------------MMSGSMLSP--------WVNAPDS 266
                      |.||.|                         |::|:.:||        |::   .
Mouse   226 QAFYFQSPSHLMHKNIPFLTKDFMITCICKYLAIDFSWKDAMLTGACISPSAWKKYEKWLS---P 287

  Fly   267 DGIFCRLATSAGYEGPAEEVPILE--FLR-----NVNAEKLIGHDFI 306
            |.|..|..|:  |:.|....|..|  :|.     |::...|:..|.|
Mouse   288 DNIPKRFRTT--YQPPESPAPFNEAAYLETKHAMNIDISPLVADDKI 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	53/242 (22%)
Aadacl4fm1	NP_941064.2	alpha/beta hydrolases	115..380	CDD:473884	51/236 (22%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	119..121		0/1 (0%)