Protein Alignment alpha-Est6 and CG4382

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Alignment Length: 624
• Identity: 191/624 - (30%)
• Similarity: 289/624 - (46%)
• Gaps: 115/624 - (18%)

  Fly     1 MWKLCQPRSRSRIKCFRFLILRCCPGFKRFSCQSAGDADSK------------------VVKLSV 47
            ||:||           .|::|.|  |..  |.|::.:..||                  |:..::
  Fly     1 MWRLC-----------GFVLLLC--GLA--SGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTAL 50

  Fly    48 GSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGK 112
            |.::|..|....|..||:|.|||:||||:.:.||...:..:.|...|||..:.|...|:...||.
  Fly    51 GKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLVSGD 115

  Fly   113 VVGSEDCLYLNVYTKHF-NESEPPL--PVMVYIY-GGAFRTGGAVKSKYGPDYLMSRDVVYVLFN 173
            |  |||||.:|:|||.. :||:|.:  ||:|:|: ||.:...|..|:..||.|.|:|.:|.|.||
  Fly   116 V--SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFN 178

  Fly   174 YRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMC 238
            |||.|||||:  :|..:.|||.||.||:..|:||..||..|.|||.:|||.|..|||.:|...|.
  Fly   179 YRLGSLGFLA--TGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMV 241

  Fly   239 LPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGH 303
            .|.::|||||||:|||::...| :.||..   ..:||............:.|.:..:..:..:
  Fly   242 SPMSRGLFHKAIVMSGAVTGQW-SLPDHQ---MDVATKQATLLHCHTENVTEMMDCLKGKHYL-- 300

  Fly   304 DFISPRDRCFGF--LNP---FAPVVGG-------LVAAPFQQLMKEAWSCEVPLLLGGTSFEGLV 356
            :|.:...:.|.|  .||   :.||:..       ||..|.:....:.: .:||::.|.|..|.:
  Fly   301 EFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDF-MKVPIITGMTKDEFV- 363

  Fly   357 YYPFCQLDNGYMLELLKHEPAMVLPHELYQSM-----------------SVEERNTAADVLVKYH 404
                     |..|.:|:....:...:|.::|:                 |.|.||         |
  Fly   364 ---------GPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRN---------H 410

  Fly   405 YGPRGITKSN--ITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCG 467
            |.|..:..:|  :..:.:|:|..|...||||.|  .|:......|.|||.:...:.::    ...
  Fly   411 YFPDKLIDANRSLEALSNLYSDALTGFGIHRFV--HLAARSTKVYYYRFSYQGARSHI----YYP 469

  Fly   468 DDIKRGVCHADDLGYIFHKQAQAKQ-PLDSPEFLTIQRMVGILTTFARTGDPNCPETGPD----- 526
            :|...||.|.|||.|:|.:.:.::. ..|..||..:..||.:.:.||..||||.|   .|
  Fly   470 EDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKP---TDLALRD 531

  Fly   527 -PWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLY 564
             .|.|.|.|..: .|:||:.:.....:..:..::|.||:
  Fly   532 IRWRPFSFKKRY-YLDIGKHITLEENLNAENYEIWKRLF 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	174/558 (31%)
		Aes	<133..325	CDD:223730	76/199 (38%)
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	176/563 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467412
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	1	0.950	-	0	Normalized mean entropy	S4180
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	10	9.750