Protein Alignment alpha-Est6 and Nlg2

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Alignment Length: 588
• Identity: 149/588 - (25%)
• Similarity: 224/588 - (38%)
• Gaps: 157/588 - (26%)

  Fly    23 CCPGFKRFSCQSAGDADSKVVKLSVGSVKG--RRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQ 85
            ||      .|...|   |..||...|.::|  .|.|.:    ..:|.|||:|.||:|..||:...
  Fly   174 CC------ECLHGG---SNTVKTKYGLLRGIVVRSSPL----VEAFLGIPYASPPVGSLRFMPPI 225

  Fly    86 LADPWNSELDA-------RQERPIP--------------LQMDRRSGKVV--GSEDCLYLNVYTK 127
            ....|.:...|       .|..|||              |...||...::  .||||||||:|..
  Fly   226 TPSTWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVP 290

  Fly   128 H------------FNESEPPLPVMVYIYGGAFRTGGAVKSKY-GPDYLMSRDVVYVLFNYRLCSL 179
            :            ..|.:..|..:|:|:|.::.....  :.| |.:.....:|:.|..|:||...
  Fly   291 YETRRQRRNTDDTTGEPKTKLSTVVFIHGESYDWNSG--NPYDGSELAAHGNVIVVTINFRLGIF 353

  Fly   180 GFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKG 244
            |||. ..||....||.||.|.:..|.|:.:::..|.||||:|||.|...||...:.::..|.|..
  Fly   354 GFLK-TGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASD 417

  Fly   245 LFHKAIMMSGSMLSPWVNAPDSDGIFC--RLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFIS 307
            |..:.:::|||.||||  |...:.:|.  |:|...|..|......:...||..:..:|:......
  Fly   418 LIQRTVLVSGSALSPW--AIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAELLAVKVDH 480

  Fly   308 PRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELL 372
            ||     ||..|||.|.|.|.:|....:   .|..:||.....|..|:.|..|.:.|..:.|..:
  Fly   481 PR-----FLVGFAPFVDGTVISPGANPL---GSTTLPLGSAIVSTSGIEYANFPKRDLIFCLTSV 537

  Fly   373 KHEPAMVLPHELYQSMSVEE-----RNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIH 432
                      |.|..:|.::     ..|..|.:::             |.:.:.|.|.|  :.|.
  Fly   538 ----------ESYLDLSAQDLEFGFNETRRDRILR-------------TFVRNNFHYHL--NEIF 577

  Fly   433 RVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDD---------------IKRGVCHADDLGY 482
            .|:.:..:           |::    ..:||.|...|               ||.|..|:...|.
  Fly   578 AVLKNEYT-----------DWE----KAIRNPLSSRDATLQFLSDGHTASPLIKLGYMHSLRGGR 627

  Fly   483 IF-----HKQAQAKQPL--------DSP-------------EFLTIQRMVG-----ILTTFARTG 516
            .:     ||..:.:.|.        |.|             .:.|.:|.:|     .|:.||:||
  Fly   628 AYFLHFKHKTIEEEYPQRSGSVRGEDVPFWLGLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTG 692

  Fly   517 DPN 519
            :||
  Fly   693 NPN 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	145/572 (25%)
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	145/571 (25%)