Protein Alignment alpha-Est6 and Nlg3

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 649
• Identity: 161/649 - (24%)
• Similarity: 249/649 - (38%)
• Gaps: 175/649 - (26%)

  Fly    40 SKVVKLSVGSVKG--RRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPI 102
            |::|....|:|.|  ..|.|.:.|...:|.|:|:|.||:|..||:.......|:....|.:..|:
Mosquito    63 SRIVHTKYGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKKADRFSPV 127

  Fly   103 PLQ-----------MDRR-SGKVV-----------GSEDCLYLNVYT-----KHFNESEPPLPVM 139
            ..|           ::|. .|::.           .||||||||:|.     ...:.|.....|:
Mosquito   128 CPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSKYAVV 192

  Fly   140 VYIYGGAFRTG------GAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLD-VPGNAGL 197
            |:::|.::...      |:|.:.||       .::.|..||||..||||:....:.. .|.|.||
Mosquito   193 VFVHGESYEWNSGNPYDGSVLASYG-------QILVVTINYRLGILGFLNANVDRFSKAPANYGL 250

  Fly   198 HDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMM---CLPQAKGLFHKAIMMSGSMLSP 259
            .|.:.||.|:.::|..|.|||:::||.|...|||.|||::   .:|:.. |||:|||||||.|:|
Mosquito   251 MDIIAALHWIQENIEAFGGDPKSVTLAGHGTGAACVHFLIASAAVPEGL-LFHRAIMMSGSGLAP 314

  Fly   260 W--VNAPDSDGIFCRLATSAGYEGP----AEEVP---ILEFLRNVNAEKLIGHDFISPRDRCFGF 315
            |  |..|         |..|.|...    :.::|   :|:.||:...|     |.:|...|...|
Mosquito   315 WSLVGEP---------AKFAAYVSHHVNCSPDLPHQLLLKCLRDKPLE-----DILSTSVRAPDF 365

  Fly   316 LNPFAPVVGGLV--AAPFQQLMKEAWS-----------------------------------CEV 343
            .|.|.|.|.|:|  ....||:....:|                                   .:.
Mosquito   366 GNAFGPSVDGVVIDTGEIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINKLSKY 430

  Fly   344 PLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKY----- 403
            .||:|.|..|  .|:.|...|..|.:|..:.  |.:|.:.:..:.|.......|.::.:|
Mosquito   431 DLLVGVTRAE--AYFAFNSEDVQYGIEADRR--AKILKNYVRSTYSFHLNEILATIVNEYTDWER 491

  Fly   404 ---HYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDF-----DSPKLNL 460
               |  |..|....:..:.|.   ::....:....|....|..  ::||.||:     |.|:
Mosquito   492 PVQH--PINIRDETLEALSDA---RIVAPAVQTADLHSADHRN--SFLYVFDYQTKFGDFPQ--- 546

  Fly   461 MRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPL-----------DSPEFLTIQRMVGILTTFAR 514
                      ::|..|.:||.|:|      ..||           ...|....:.::...:.|.|
Mosquito   547 ----------RQGCIHGEDLPYLF------GAPLVGGFNHFTRNYTKSEIALSEAVMIYWSNFIR 595

  Fly   515 TGDPNCPETGPD-----------PWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLYSDL 567
            ||:|| .:...|           .|.|..:... |.||:..:.:.........|..|..|..||
Mosquito   596 TGNPN-EQLENDHVRDRTRFKNIEWTPYESVHK-KYLNLDTKPKLKNHYRAHRLSFWLNLVPDL 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	153/616 (25%)
Nlg3	XP_061500330.1	None