Protein Alignment alpha-Est6 and Ces5a

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 155/540 - (28%)
• Similarity: 229/540 - (42%)
• Gaps: 122/540 - (22%)

  Fly    47 VGSVKGRRLSGIYG--DEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIP------ 103
            :|.|:|::.: :.|  :....|.|||||.||||..||...|...||:   |.|:....|
  Rat    37 LGWVQGKQAT-VLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWH---DLREATTYPNVCFQN 97

  Fly   104 ---LQMDRRSGKV----VG-SEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTG------GAVK 154
               |.:.:...||    :| ||||||||:|...:......||||::|.||.|.||      |:..
  Rat    98 LEWLFIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFDGSAL 162

  Fly   155 SKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQ 219
            :.|       .||:.|...|||...||.:  :.....|||....|||.|||||.::|..|.|:|.
  Rat   163 AAY-------EDVLIVTIQYRLGIFGFFN--TQNQHAPGNWAFQDQLAALQWVRENINYFGGNPD 218

  Fly   220 NITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSD---GI-----FCRLATS 276
            ::|:||.||||.|:..::..|.:.||||:|||.||..:.|.:...|.:   |:     .|:...|
  Rat   219 SVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVS 283

  Fly   277 AGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCF-----GFLNPFAPVVGGLVAAPFQQLMK 336
                   :...:|:.||..::.:|:.   :..:.:.|     |...|..|:          :|:.
  Rat   284 -------DSKVLLKCLREKSSLELLS---LGQKTKAFTRVVDGSFFPEEPM----------ELLS 328

  Fly   337 EAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYML------ELL---KHEPAMVLPHELY----QSM 388
            :.....||.::|..:.|       |    ||:|      |:|   ....|:.|.|.|.    |.|
  Rat   329 QKTFKTVPSIIGVNNQE-------C----GYILPMREAPEILFGSNESTALTLIHVLLHIPPQYM 382

  Fly   389 SVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQA--PTYLYRF 451
            .:        |...|.:|...:|....| :||||....|  .:..:|.:| :|..|  |.|.|.|
  Rat   383 HI--------VAKDYFHGKHSLTDIRDT-LLDLFGDVFF--VVPGLVTAR-NHRDAGGPVYFYEF 435

  Fly   452 DFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIF-----HKQAQAKQPLDSPEFLTIQRMVGILTT 511
            ..........|......|      |.|::.::|     .......:.....|.|..::|:.....
  Rat   436 QHRPNCFQNTRPAFVKAD------HTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWAN 494

  Fly   512 FARTGDPNCPETGPD-PWMP 530
            |||:||||    |.| |..|
  Rat   495 FARSGDPN----GDDLPLWP 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	155/540 (29%)
		Aes	<133..325	CDD:223730	66/210 (31%)
Ces5a	NP_001012056.2	Esterase_lipase	40..529	CDD:238191	154/537 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740