Protein Alignment alpha-Est6 and Ces1e

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_113753.2
• Gene: Ces1e / 29225
• RGDID: 621508
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 183/596 - (30%)
• Similarity: 261/596 - (43%)
• Gaps: 96/596 - (16%)

  Fly    15 CFRFLILRCCPGFKRFSCQSAGDADSK--VVKLSVGSVKGR--RLSGIYGDEFYSFEGIPFAKPP 75
            |...|||.....|      :||...|.  ||....|.|.|:  .|.| :......|.|:||||||
  Rat     2 CLYALILVFLAAF------TAGGHPSSLPVVDTLQGKVLGKYVSLEG-FTQPVAVFLGVPFAKPP 59

  Fly    76 LGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVG--------------SEDCLYLNVYT 126
            ||..||...|.|:||:...:.....|:..| |..:|::|.              ||||||||:||
  Rat    60 LGSLRFAPPQPAEPWSFVKNTTSYPPMCSQ-DPVAGQIVNDLLTNREENISLQFSEDCLYLNIYT 123

  Fly   127 KHFNESEPPLPVMVYIYGGAFRTGGAVKSKY-GPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLD 190
            .........|||||:|:||....|||  |.| |.......:||.|:..|||...||.|  :|...
  Rat   124 PADLTKRDRLPVMVWIHGGGLVLGGA--STYDGLALSTHENVVVVVIQYRLGIWGFFS--TGDEH 184

  Fly   191 VPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGS 255
            ..||.|..||:.||.||..:|.||.|||.::|:||||||..||..::..|.||.||||||..||.
  Rat   185 SRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHKAISESGV 249

  Fly   256 MLSPWV----NAPDSDGIF----CRLATSAGY-----EGPAEEVPILEFLRNVNAEKLIGHDFIS 307
            .|:..:    ..|.::.|.    |:..|||..     :...||  :||....:|   |...|...
  Rat   250 ALTAGLVKKNTRPLAEKIAVVSGCKSTTSAAMVHCLRQKTEEE--LLETTLKLN---LFSLDLHG 309

  Fly   308 PRDRCFGFLNPFAP-VVGGLVAAPF-QQLMKEAWSCEVPLLLG------GTSFEGLVYYP--FCQ 362
            ...:.:    ||.| |:.|:|.... ::::.|.....||.::|      |.....::.||  ..:
  Rat   310 DSRQSY----PFVPTVLDGVVLPKMPEEILAEKDFNTVPYIVGINKQEFGWILPTMMNYPPSDMK 370

  Fly   363 LDNGYMLELLKHEPAMV-LPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKL 426
            ||......|||....:: ||.|            |..|.|:.:.........|..|:|:|....:
  Rat   371 LDPMTATSLLKKSSFLLNLPEE------------AIPVAVEKYLRHTDDPDRNKDQLLELIGDVI 423

  Fly   427 FWHGIHRVVLSRLSH--AQAPTYLYRFDFDSPKLNLMR-NQLCGDDIKRGVCHADDLGYIFHKQA 488
            |  |:..|::|| .|  |.|.||:|.|.:.....:.|: :.:.||       |.|::..:|  .|
  Rat   424 F--GVPSVIVSR-GHRDAGARTYMYEFQYRPSFSSKMKPSTVVGD-------HGDEIYSVF--GA 476

  Fly   489 QAKQPLDSPEFLTIQR-MVGILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQV 552
            ...:...|.|.:.:.: |:.....|||.|:||  ..|...|.....|..:  |.||...:...::
  Rat   477 PILRGGTSKEEINLSKMMMKFWANFARNGNPN--GQGLPHWPEYDQKEGY--LQIGATTQQAQKL 537

  Fly   553 EKDGLKVWNRL 563
            ::..:..|:.|
  Rat   538 KEKEVAFWSEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	171/543 (31%)
Ces1e	NP_113753.2	COesterase	24..545	CDD:395084	173/563 (31%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561