Protein Alignment alpha-Est6 and Ces4a

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 166/556 - (29%)
• Similarity: 252/556 - (45%)
• Gaps: 79/556 - (14%)

  Fly    48 GSVKGRRLSGIYGD-EFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSG 111
            |.::|:::.  .|| ....|.|:||::||:|..||...:...|||...||....|..||  ...|
  Rat    41 GILQGKQVH--VGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQ--ESWG 101

  Fly   112 KVVG--------------SEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYL 162
            ::..              ||||||||||.......:|.|||||:..||||..|.|  |.|....|
  Rat   102 QITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSA--STYEGSEL 164

  Fly   163 MSR-DVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGE 226
            .:| .||.|...|||..|||.|  :|.....||.||.||:.||:||.::|..|.|||.::||||:
  Rat   165 AARGKVVLVFLQYRLGILGFFS--TGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQ 227

  Fly   227 SAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEF 291
            ||||.||..::..|.|:||||:||..||:.:.......|......::|..||.:..:.:: :::.
  Rat   228 SAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKI-MVKC 291

  Fly   292 LRNVNAEKLI----------GHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQ----LMKEAWSCE 342
            |:.:.|||::          .:....|:|..: ||   :|||.|||   |.:    |:.......
  Rat   292 LKALPAEKVMLVSKKMTFFRANSHKDPKDIVW-FL---SPVVDGLV---FPEDPVVLLTRGQVKP 349

  Fly   343 VPLLLGGTSFEGLVYYPFCQ--------LDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADV 399
            ||.|||..|.|.....||..        ::..|:.:||  ....:|.:...:.:.:..|...:|.
  Rat   350 VPYLLGVNSAEFEWSLPFLMKLQLNQRIMNKNYITKLL--WSCSILLNITEEQIPLVAREYLSDA 412

  Fly   400 LVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSH--AQAPTYLYRFDFDSPKLNLMR 462
            :..:.:      |.....::||.....|   ::..:.:...|  |.:|.|||.|...:|.: :::
  Rat   413 ISHHDW------KMFRNHLIDLVGDATF---VYATLQAARYHRDAGSPVYLYEFKHHAPGI-IVK 467

  Fly   463 NQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGPDP 527
            .:..|.|      |.|:|.|:|.............:..::| |:.....||.|||||..|.   |
  Rat   468 PRSDGAD------HGDELSYLFGSPFSKGSSRGEEKEFSLQ-MMKYWANFAHTGDPNDREL---P 522

  Fly   528 WMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRL 563
            :.|...|.. |.|.:........::.:..:..|.||
  Rat   523 YWPRFDKEE-KYLQLDFDTRVGVKLREKQMTFWRRL 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	161/527 (31%)
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	163/551 (30%)