Protein Alignment alpha-Est6 and cest-9.2

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 129/538 - (23%)
• Similarity: 198/538 - (36%)
• Gaps: 152/538 - (28%)

  Fly    41 KVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQ 105
            ||::.|.|.|:|........:..|.|:.:||||||:||.||...|..|.|:..|||.:..|..|.
 Worm    22 KVIETSYGRVRGITEWSDDNNHKYMFKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYSPACLS 86

  Fly   106 MDRRSG--KVVGSEDCLYLNVYTKHFNESEPPL----PVMVYIYGGAFRTGGAVKSKYGPDYLMS 164
            ....:.  :...||||||:|::|     ||..|    .|:||.:|||:  .|...:.:..::::.
 Worm    87 NSSTTSTPQEHVSEDCLYINIFT-----SEKCLRSKCAVIVYFHGGAY--NGDSATMFPDNFILE 144

  Fly   165 R----DVVYVLFNYRLCSLGFLSM-PSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLF 224
            |    ||:..:...||...|.|.. ||..|  ..|..:.|.:.||.:|...|.||.|||:.:|:.
 Worm   145 RYVAEDVILAIPGVRLGVFGQLYFGPSALL--TENLFMFDAVQALDFVHNEIPNFGGDPKQVTIM 207

  Fly   225 GESAGAASVH---FMMCLPQAKGLFHKAIMMSGS-MLSPWVNAPDSDGIFCRLATSAG-YEGPAE 284
            |.|:|...|.   |...:.....||.:.|::||: |...:....|:..|   ::...| :.|..|
 Worm   208 GHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYDLLVDNSFI---ISEKLGCFNGTQE 269

  Fly   285 E------VPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEV 343
            |      ..|||.:|.::..:::|                            .|:.|::.:....
 Worm   270 ERTDANIAEILECMRQIDGHEIVG----------------------------MQKHMEDVYKLTF 306

  Fly   344 PLLLGGTSFE--------------------GLVYYPFCQLDNGYM---LELLKHE-PAMVLPH-- 382
            ..||.|..|.                    |...|.|......|:   ...|..| |..|..|
 Worm   307 KSLLRGAPFMELNGKIEKFRNSTSPRNAIFGTTEYEFRNEVERYLYITTTFLDFENPVAVAQHFD 371

  Fly   383 -ELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPT 446
             ||.|:|.......|..:.|.                ...||             |.:::|.|..
 Worm   372 DELMQNMDTMINGDAVSIFVS----------------AAAFS-------------SAMANAGADV 407

  Fly   447 YLYR-----FDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYI--FHKQAQAKQPLDSPEFLTIQR 504
            ||:.     :.|                      |..|:.|.  .|::......:|..:....:
 Worm   408 YLFETRQWPYSF----------------------HVSDMQYFIGIHREVLHTHDMDILDSFYSK- 449

  Fly   505 MVGILTTFARTGDPNCPE 522
               :|..|.:||.|: ||
 Worm   450 ---LLVNFTKTGAPS-PE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	129/538 (24%)
		Aes	<133..325	CDD:223730	53/211 (25%)
cest-9.2	NP_741910.3	Abhydrolase	19..501	CDD:304388	129/538 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.830