Protein Alignment alpha-Est6 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 602
• Identity: 158/602 - (26%)
• Similarity: 245/602 - (40%)
• Gaps: 162/602 - (26%)

  Fly    26 GFKRFSCQSAGDADSKVVKLSVGSVKGRRL---SGIYG--DEFYSFEGIPFAKPPLGKARFVASQ 85
            ||.....:::..|.:..|....|.::|.|:   |.|.|  |::.   |:|:|.||:|:.||:..:
Mouse    24 GFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYL---GVPYAAPPIGEKRFLPPE 85

  Fly    86 LADPWNSELDARQERPI-PLQMDRRSGKVV------------------GSEDCLYLNVYT----- 126
            ....|:...:|....|: |..:.....:|:                  .:|||||||||.
Mouse    86 PPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDG 150

  Fly   127 ------------KHFNESEP-----PLPVMVYIYGGAFRTG------GAVKSKYGPDYLMSRDVV 168
                        ...:|.|.     ..||||||:||::..|      |:|.:.||       :|:
Mouse   151 SGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------NVI 208

  Fly   169 YVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASV 233
            .:..|||:..|||||  :|.....||.||.||:.||:|||::|..|.|||:.||:||...||:.|
Mouse   209 VITLNYRVGVLGFLS--TGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCV 271

  Fly   234 HFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPD-------SDGIFCRLATSAGYEGPAEEVPILE 290
            ..:.....::|||.:||:.|||.||.| ||...       :|.:.|.:         .:.|.:::
Mouse   272 SLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNV---------LDTVDMVD 327

  Fly   291 FLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVV-GGLVAAPFQQLMKEAWSCEVPLLLGGTSFEG 354
            .||..:|::|:..|....|     :...|.||: |.::....:.||::.......::||....||
Mouse   328 CLRQKSAKELVEQDIQPAR-----YHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEG 387

  Fly   355 LVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYG-PRGITKSNITQI 418
                             ||....:|.|.:   .:|..:.:.:....|...|| |.|  |..:.:.
Mouse   388 -----------------LKFVEGVVDPED---GVSGTDFDYSVSNFVDNLYGYPEG--KDTLRET 430

  Fly   419 LDLFSY-----------------KLF----WHGIHRVVLSRLSHAQ--APTYLYRFDFDSPKLNL 460
            :. |.|                 .||    |  :...|::...||:  :|||.|.|
Mouse   431 IK-FMYTDWADRDNPETRRKTLVALFTDHQW--VEPSVVTADLHARYGSPTYFYAF--------- 483

  Fly   461 MRNQLCGDDIK---RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGIL-----TTFARTGD 517
              ...|...:|   ....|.|::.|:|.........|....|.....|:..:     |.||:|||
Mouse   484 --YHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGD 546

  Fly   518 PNCPETGPDPWMPVSTK 534
            ||.|       :|..||
Mouse   547 PNKP-------VPQDTK 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	154/591 (26%)
		Aes	<133..325	CDD:223730	72/211 (34%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	155/587 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832446
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740