Protein Alignment alpha-Est6 and Ces4a

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 576
• Identity: 172/576 - (29%)
• Similarity: 250/576 - (43%)
• Gaps: 109/576 - (18%)

  Fly    48 GSVKGRRLSGIYGD-EFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSG 111
            |.::|:::.  .|| ....|.||||:|||:|..||...:...|||...||....|..||  ...|
Mouse    41 GILQGKQVH--VGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQ--ESWG 101

  Fly   112 KVVG--------------SEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYL 162
            :::.              ||||||||||........|.|||||:..||||..|.|  |.|....|
Mouse   102 QILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSA--STYEGSEL 164

  Fly   163 MSR-DVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGE 226
            .:| .||.|...|||..|||.|  :|.....||.||.||:.||:||.::|..|.|||.::||||:
Mouse   165 AARGKVVLVFLQYRLGILGFFS--TGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQ 227

  Fly   227 SAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEF 291
            ||||.||..:|..|.|:||||:||..||:.:......||......::|..||.:..:.:| ::|.
Mouse   228 SAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKV-MVEC 291

  Fly   292 LRNVNAEKLIGHDFISPRDRCF---GFLNP------FAPVVGGLVAAPFQQ----LMKEAWSCEV 343
            ||:::||::   ..:|.|...|   ...:|      .:|||.|:|   |.:    |:.......|
Mouse   292 LRSLSAEEV---TLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVV---FPEDPVVLLTRGQVKPV 350

  Fly   344 PLLLGGTSFEGLVYYPF---CQLDNGYM---------------LELLKHEPAMVLPHELYQSMSV 390
            |.|||..:.|.....||   .||:...|               |.:.|.:..:|....|..::|.
Mouse   351 PYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISN 415

  Fly   391 EE----RNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSH--AQAPTYLY 449
            .:    ||                      :::||.....|   ::..:.:...|  |.:|.|||
Mouse   416 HDWKMFRN----------------------RLIDLIGDATF---VYATLQAARYHRDAGSPVYLY 455

  Fly   450 RFDFDSPKLNLMRNQLCGDDIK--RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTF 512
            .|...:..         |..||  .|..|.|:|.|:|.............:..::| |:.....|
Mouse   456 EFKHHASS---------GIIIKPYNGADHGDELSYLFGSPFSKGSSAGEEKEFSLQ-MMKYWANF 510

  Fly   513 ARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLYSDLK 568
            |.||:||..:.   |:.|...|.. |.|.:........::::..:..|::|....|
Mouse   511 AHTGNPNGEKL---PYWPRFDKDE-KYLQLDFDTRVGVKLKEKKMAFWSQLRQSQK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	166/540 (31%)
		Aes	<133..325	CDD:223730	81/201 (40%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	169/566 (30%)
		Aes	<128..>272	CDD:223730	67/147 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750