Protein Alignment alpha-Est6 and Ces1f

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 585
• Identity: 175/585 - (29%)
• Similarity: 257/585 - (43%)
• Gaps: 103/585 - (17%)

  Fly    31 SCQSAGDADS-KVVKLSVGSVKGRRLS--GIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNS 92
            :|...|:..| .||..:.|.|.|:.::  | :......|.||||||||||..||...|.|:||:|
Mouse    13 TCVICGNPSSPPVVDTAHGKVLGKHVNVEG-FSQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWSS 76

  Fly    93 ELDARQERPIPLQMDRRSGKVVG--------------SEDCLYLNVYTKHFNESEPPLPVMVYIY 143
            ..:|....|:..| |...|:.|.              ||||||||:||.........|||||:|:
Mouse    77 VKNATTYPPMCSQ-DAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSKNSRLPVMVWIH 140

  Fly   144 GGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVS 208
            ||..:.||| .|..|.......:||.|...|||...||.|  :|.....||.|..||:.||.||.
Mouse   141 GGGLKLGGA-SSFDGRALSAYENVVVVAIQYRLSIWGFFS--TGDEHSRGNWGHLDQVAALHWVQ 202

  Fly   209 QHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRL 273
            .:|.||.|||.::|:||||||..||..::..|.:|.|||:||..||....|.:...|...|..::
Mouse   203 DNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFTKDVRPITEQI 267

  Fly   274 ATSAGYEGPAE-----------EVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLV 327
            |.:||.:....           |..:||.:..:|..||.........|:   |:   ..|:.|:|
Mouse   268 AVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQGDTKNSDQ---FV---TSVLDGVV 326

  Fly   328 AA--PFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFC---------------QLDNGYMLELLKHE 375
            ..  | ::::.|.....||.::|....|       |               :||....:.||:..
Mouse   327 LPKDP-KEILAEKNFNTVPYIVGINKQE-------CGWLLPTMTGFLPADVKLDKKKAIALLEQF 383

  Fly   376 PAMV-LPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRL 439
            .:|. :|.::. .::||:....:|       .|..|.:.    :||......|  |:..|::||
Mouse   384 ASMTGIPEDII-PVAVEKYTKGSD-------DPDQIREG----VLDAMGDVAF--GVPSVIVSR- 433

  Fly   440 SHAQ--APTYLYRF----DFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPE 498
            .|..  ||||:|.:    .|.||:   ....:.||       ||||:..:|  .|...:...|.|
Mouse   434 GHRDTGAPTYMYEYQYYPSFSSPQ---RPKNVVGD-------HADDVYSVF--GAPILREGASEE 486

  Fly   499 FLTIQRMV-GILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNR 562
            .:.:.:|| .....|||.|:||  ..|...|.....|..:  |:||...:...:::::.:..|.:
Mouse   487 EINLSKMVMKFWANFARNGNPN--GKGLPHWPKYDQKEGY--LHIGGTTQQAQRLKEEEVTFWTQ 547

  Fly   563  562
            Mouse   548  547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	169/551 (31%)
		Aes	<133..325	CDD:223730	71/202 (35%)
Ces1f	NP_659179.1	COesterase	24..545	CDD:278561	171/570 (30%)
		Aes	<121..>225	CDD:223730	47/106 (44%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832957
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750