Protein Alignment alpha-Est6 and Aadacl3

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001078972.1
• Gene: Aadacl3 / 230883
• MGIID: 2685281
• Length: 408
• Species: Mus musculus
• Alignment Length: 311
• Identity: 61/311 - (19%)
• Similarity: 101/311 - (32%)
• Gaps: 107/311 - (34%)

  Fly    68 GIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNES 132
            |:.|.|..|..|...||.|.|               |:..:|...|| .:|..:..:..|.:...
Mouse    58 GMIFEKLGLCYAPQFASFLHD---------------LKPLKRDPDVV-VKDLHFGTIPVKLYKPK 106

  Fly   133 EP---PLPVMVYIYG-----GAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKL 189
            :|   |...:::.:|     |:.||..::..:...:.    |.|.|       |:|:...|..|.
Mouse   107 KPSSIPRLGIIFFHGGGTIIGSLRTHNSICLRLSKEC----DSVVV-------SVGYRKSPMYKY 160

  Fly   190 DVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAG--AASVHFMMC-----LPQAK---- 243
            .|..:    |.::|.....:.:..:..||..:...|:|.|  ||:|...|.     ||:.|
Mouse   161 PVMKD----DCVVATTHFLESLDVYGVDPARVVTCGDSVGGTAATVTSQMLVHRPDLPRIKAQIL 221

  Fly   244 ---------------------------------------GLFHKAIMMSGSMLSP--------WV 261
                                                   .:..|:::.:|..|.|        |:
Mouse   222 IYPLLQLIDFGSPSYQQNRNIPLLSWDLAFYCFCCHLDVNISWKSVVKNGMHLPPDVWEKYRKWL 286

  Fly   262 NAPDSDGIFCRLATSAGYE----GPAEEVPILEFLRNVN--AEKLIGHDFI 306
            .|.:....|    .:.||:    ||.......|..|::|  ...||..|.|
Mouse   287 GAENIPERF----KNRGYKSIPWGPVNNDAYQEIKRSLNYTCSPLISEDSI 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	61/311 (20%)
Aadacl3	NP_001078972.1	Abhydrolase_3	116..379	CDD:400284	44/237 (19%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	120..122		0/1 (0%)