Protein Alignment alpha-Est6 and Ces2e

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 165/561 - (29%)
• Similarity: 248/561 - (44%)
• Gaps: 74/561 - (13%)

  Fly    32 CQSAG-DADSKVVKLSVGSVKGRRL------SGIYGDEFYSFEGIPFAKPPLGKARFVASQLADP 89
            ||..| |:.|.:.....|.|:|..:      ||:     ::|.||||||||:|..||...:..:|
  Rat    22 CQVQGQDSASPIRNTHTGQVRGSFVHVKDTKSGV-----HTFLGIPFAKPPIGPLRFAPPEPPEP 81

  Fly    90 WN-------------SELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVY 141
            |:             ..:|......:.::|.|  ..|..|||||||::||......:..|||||:
  Rat    82 WSGVRDGTSHPAMCLQNIDGLNLENLKIKMSR--SPVSMSEDCLYLSIYTPAHTHKDSNLPVMVW 144

  Fly   142 IYGGAFRTGGAVKSKYGPDYLMS-RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQ 205
            |:||....|.|  |.|....|.: .|||.|...|||..|||.|  :|.....||.|..||:.||:
  Rat   145 IHGGGLCWGMA--STYDGSMLAAIEDVVVVTIQYRLGILGFFS--TGDEHARGNWGYLDQVAALR 205

  Fly   206 WVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIF 270
            ||.|:|.:|.|:|..:|:||||||..||...:..|.::||||.|||.||..|.|.:.:..|:.|:
  Rat   206 WVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIY 270

  Fly   271 CRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPF---- 331
            ..:|..:|.| |.:...::..||..:.|:::.             :|.....:.|:|...|
  Rat   271 TMVANLSGCE-PVDSEALMSCLREKSEEEMLA-------------INNIVRTISGVVDGKFLPRH 321

  Fly   332 -QQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNT 395
             .:|:.......||.::|..|.|.....|....|: .|.|:.:.....||.:...|.|...|
  Rat   322 PLELLASVDFHPVPSIIGINSDEYGWIIPMLHPDS-TMKEINRETMRAVLKNTAVQMMLPPE--- 382

  Fly   396 AADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNL 460
            .:|:|::.:.|....:|:...|..::....:|  .|..:.::....:.||.|.|.|...|..|..
  Rat   383 CSDLLMEEYMGDTEDSKTLQIQFNEMMGDFIF--VIPALQVAHFQRSHAPVYFYEFQHQSNFLKD 445

  Fly   461 MRNQLCGDDIKRGVCHADDL----GYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCP 521
            :|......|      |.|:|    ||:|.   ..|......|.|..::|:.....|||.|:||
  Rat   446 IRPPHVKAD------HGDELPYVIGYLFW---DMKFVFTEEEKLLSRKMIKYWANFARHGNPN-- 499

  Fly   522 ETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNR 562
            ..|...|..:.....:..|:|...|....:..:  ||.|.:
  Rat   500 SEGLPYWPALDHDEQYLQLDIQPVVGRALKARR--LKFWTK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	155/525 (30%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:395084	160/549 (29%)