Protein Alignment alpha-Est6 and cest-28

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 147/548 - (26%)
• Similarity: 241/548 - (43%)
• Gaps: 98/548 - (17%)

  Fly    40 SKVVKLSVGSVKGRRLSGIY--GDEFY-SFEGIPFAKPPLGKARFVASQLADPWNSELDAR---- 97
            |:.:..:.|.::|    .:|  ||:.. .:.|||||||   ..||...:.|..|....|..
 Worm    14 SEKLNATCGPIQG----NVYRIGDKTVDGYLGIPFAKP---LVRFKKPEPAGTWEEVRDCTKYGP 71

  Fly    98 ---QERPIPLQMDRRSGKVVGSEDCLYLNVY-----TKHFNESEPPLPVMVYIYGGAFRTGGAVK 154
               |..|....::.:...:....:||.|||:     :|:||::.   ||||||:||.:....
 Worm    72 RCPQSGPFAEAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTR---PVMVYIHGGGYECSA--- 130

  Fly   155 SKYGPDY-----LMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNF 214
            |:...||     |..:|||.|..|||:..|||.:  :|....|||..|.|..|.|.|:.:||.:|
 Worm   131 SRDYCDYSVAGTLPLKDVVVVTLNYRVGILGFFT--TGDTVCPGNFALWDLTLGLNWIQKHIESF 193

  Fly   215 NGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPDSDGIFC-RLATSA 277
            .|||.|||:||:|||||.|..:...|.::.||::.|:|||..|..: |...:|....| ..|...
 Worm   194 GGDPGNITIFGQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHL 258

  Fly   278 GYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGL---------------- 326
            ||:|...:. :..::::...|::         ::..||..|.:.::...
 Worm   259 GYDGTNSQT-LFNWMKSKPLEEI---------EKMNGFQVPASGILAWTPNLDDDFFPKSLDELR 313

  Fly   327 VAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVE 391
            :.||.:.:|           :|....||| ::.|...|....||.||     :..:|.|:..:.:
 Worm   314 IGAPKKDIM-----------MGFAEHEGL-FFEFLIKDPTPPLEALK-----LYVNEYYKKDTGD 361

  Fly   392 ERNTAADVLVKYHYGPRGI----TKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFD 452
            ......:.:::::  .|.:    .||...:::|.....||..|:.....:.|.|.. ..:||.||
 Worm   362 HFEATRNKIIEFY--SRNVEDTDEKSTKERLIDFVGDALFTAGVFDNAKNCLKHGN-NVWLYIFD 423

  Fly   453 FDSPKLNLMRNQLCGDDIKRGVC--HADDLGYIFHKQAQAK-QPLDSPEFLTIQRMVGILTTFAR 514
            :.:|  :...||   ::....|.  |..||.|:..:...:. ||.:. |...|::|..|.:.||:
 Worm   424 YCNP--SGFGNQ---EEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEE-EHKMIEKMTTIYSNFAK 482

  Fly   515 TGDPNCPETGPDPWMPVSTKSPFKALNI 542
            .|:||  |.|...|...:..:|.:...|
 Worm   483 YGNPN--EHGSSEWEKFTLDNPRRHFQI 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	145/540 (27%)
cest-28	NP_504691.2	COesterase	17..526	CDD:395084	146/545 (27%)