Protein Alignment alpha-Est6 and cest-30

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 153/578 - (26%)
• Similarity: 240/578 - (41%)
• Gaps: 100/578 - (17%)

  Fly    37 DADSKVVKLSVGSVKGRRLSGIYGDEFY-SFEGIPFAKPPLGKARFVASQLADPWNSELDARQER 100
            :.:|:::....|.::|.......|.:.. .:.||||||.|:|..:|.....|:.|....|..:..
 Worm    28 EKNSQILNAPCGPIRGNIYKHKNGTKIVDGYLGIPFAKAPVGALKFKKPVAAEKWTEPRDCYEYG 92

  Fly   101 PIPLQMDR------RSGKVVGSEDCLYLNVYTKHFNESEPP--LPVMVYIYGGAFRTGGAVKSKY 157
            |...|..|      :|......|:||.|||:...:..:|.|  |||:||||||.:..|   .:.|
 Worm    93 PGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGLPVLVYIYGGGYEIG---FTSY 154

  Fly   158 GPDYLMS-----RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGD 217
            ..||.::     :||:.|..||||..||||::..|..:  ||.||.||.||||||..:|.:|.|:
 Worm   155 MDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIAN--GNYGLWDQTLALQWVQDNIASFGGN 217

  Fly   218 PQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAP-DSD-GIFCRLATSAGYE 280
            |:::||.|.||||.|..|:...|.:..||.::|.|||:....:...| |.: |:....|...||.
 Worm   218 PESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAIRPKDVEVGVCKEFAQFQGYT 282

  Fly   281 GPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLN------PFAP-VVGGLVAAPFQQLMKEA 338
            | .:...:.::....|..|.         ....||.:      ||.| ..|.....||..|.:||
 Worm   283 G-TDSQSLFDWYMAQNVSKF---------KEVAGFQSTAAGAVPFIPNFDGDFFPKPFDILRREA 337

  Fly   339 WSCEV----------------PLLLGG-TSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQ 386
            ...:.                ||.... .:|||.:...:......|..::.|......|     :
 Worm   338 PKKDALITVVTMESVGMIIFNPLFANAYNNFEGFINETYGPDVTDYYADVKKKLTGFYL-----K 397

  Fly   387 SMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRF 451
            .::..::.|..                  .:::|..|..:|..|....|.|.:.:.. ..||..|
 Worm   398 DVNASDKATVN------------------RRVVDYVSDSVFNSGTLDAVKSYVKYGN-KVYLGSF 443

  Fly   452 DF--DSPK--LNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAK-QPLDSPEFLTIQRMVG-ILT 510
            ::  |:.|  :.||:.       .:...|:.|..|.|.....|. .|.|  |.:.:..|.| ::.
 Worm   444 NYFNDATKDMVELMQP-------FKEASHSSDFKYYFGSGVMANFTPTD--EEMEVMDMSGTLMA 499

  Fly   511 TFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWN-RLYSDL 567
            .|.:.|||| .::|..||.|.:...|    |:..:::..|....|..:... |:|.|:
 Worm   500 NFVKYGDPN-GKSGTKPWKPYTILKP----NMYYKIDYPTCEMSDNFQNGRLRIYDDI 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	146/542 (27%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	150/569 (26%)