Protein Alignment alpha-Est6 and cest-13

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 148/533 - (27%)
• Similarity: 217/533 - (40%)
• Gaps: 94/533 - (17%)

  Fly    48 GSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGK 112
            ||...|.:...||.   ||.||.:|:||:|..||.|::..||... ::|:....|.:|.|.|:
 Worm    32 GSATIRGIQHTYGT---SFRGIRYAQPPVGLFRFGAARRLDPVGL-VEAQAYGNICVQGDGRT-- 90

  Fly   113 VVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAF-RTGGAVKSKYGPDYLMSRDVVYVLFNYRL 176
              ..||||::||||.:.......|||.|||:||.| ..||.:.:...|:.:....:|.|..||||
 Worm    91 --SHEDCLFINVYTPNNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNKGPIVMVSINYRL 153

  Fly   177 CSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQ 241
            ...||.|  :.::..|||..:.|.:.||.||.::|..|.|||..:|:.|:|:||.:|..:...|.
 Worm   154 GPFGFFS--TRQMTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQSSGAEAVSTLTLTPL 216

  Fly   242 AKGLFHKAIMMSGSMLSPWV------NAPDSDGIFCRL--ATSAGYEGPAEEVPILEFLRNVNAE 298
            ||.||.::|..|||.....|      ....|..:..:|  |||..::.......||..||||..:
 Worm   217 AKNLFKQSIHESGSAFGAAVMSYSEKTRSTSKQLSIKLGCATSDQWDNGQSFGTILTCLRNVTYD 281

  Fly   299 KLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSC--------------------EV 343
            |::..|...|..|                       ||  ||.                    :.
 Worm   282 KIVAADNSLPGHR-----------------------MK--WSIVQDNKYLTQRLEYLALQRDPKK 321

  Fly   344 PLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLV----KYH 404
            .:|:|....|.|.:    :::|........|..|..:..:|..|..:...:....|||    ||
 Worm   322 NVLIGDVHDEWLGW----EMNNVLHNINSSHNTAHQMRDDLSGSYEMTYWDNKQSVLVAADNKY- 381

  Fly   405 YGPRGITKSN----ITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQL 465
            ...:|.|..|    ..:.:.|:|..:|.....|.. :...:.:...|||..|:.||.    ...|
 Worm   382 INNQGWTDDNHREWEARRIQLWSEMVFIGPTLRDA-AYFQYMKNNVYLYSLDWLSPP----ALPL 441

  Fly   466 CGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTT----FARTGDPNCPETGPD 526
            ..|.:.||..|..:|.|||.............|.|.     ...||    |...|:|. |...|.
 Worm   442 VTDPLFRGCEHTWELQYIFSTSCNGFTCTAQDEILR-----NYFTTTWLNFIIGGNPT-PAGSPL 500

  Fly   527 P--WMPVSTKSPF 537
            |  |:.:.:.:.|
 Worm   501 PFKWLAMDSTNRF 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	147/530 (28%)
cest-13	NP_741921.1	alpha/beta hydrolases	24..526	CDD:473884	148/533 (28%)