Protein Alignment alpha-Est6 and cest-9.1

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 131/558 - (23%)
• Similarity: 218/558 - (39%)
• Gaps: 145/558 - (25%)

  Fly    18 FLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFV 82
            ||::...|.|:..          ||::.|.|.::|..:.....:..|.|:.:||||||:|..||.
 Worm     6 FLLILFIPQFQSL----------KVIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFA 60

  Fly    83 ASQLADPWNSELDARQERPIPLQMDRRSG--KVVGSEDCLYLNVYT--KHFNESEPPLPVMVYIY 143
            ..|..:.|:..|||.:..|..:.....:.  :...||||||:|::|  |..|..   .||:||.:
 Worm    61 KPQNPESWSGILDASKYSPACMSNSSSTSTPQKHYSEDCLYINIFTSEKCLNSK---CPVIVYFH 122

  Fly   144 GGAFRTGGAVKSKYGPDYLMSR----DVVYVLFNYRLCSLGFLSM-PSGKLDVPGNAGLHDQLLA 203
            |||:....|:  .:...:::.|    |||:|:...||...|.|.. ||..|.  .|..|:|.:.|
 Worm   123 GGAYNLDSAI--MFNDTFILDRYAAEDVVFVIPAVRLGVFGQLYFGPSDLLS--ENLFLYDAVQA 183

  Fly   204 LQWVSQHIRNFNGDPQNITLFGESAGAASVH---FMMCLPQAKGLFHKAIMMSGSMLSPWVNAPD 265
            |.:|...|..|.||.:.:|..|.|:|...|.   |...:.....||.:.|::|.:.:..:.:..
 Worm   184 LSFVHSEINYFGGDSKRVTAMGHSSGGTIVDALGFSKLIDPGVKLFQQMIVLSATGMFGFYDMV- 247

  Fly   266 SDGIFCRLATSAGYEGPAEEVP------ILEFLRNVNAEKLI---GH-DFISPRDRCFGFLNPFA 320
            .|..|..:.....|.|..::.|      :|:.:|.::..:::   .| :.:..||        |.
 Worm   248 VDNSFAIVEKFGCYNGTKDDRPNANIAEMLDCMRQIDGREMLLMQRHMEEVDDRD--------FR 304

  Fly   321 PVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELY 385
            .|:.|   |||.:                              .||.:.:|.|..|:..|   ||
 Worm   305 SVLRG---APFLE------------------------------SNGKIADLKKSPPSRNL---LY 333

  Fly   386 QSMSVEERNTAADVLVKYHYG-------PRGITK-------SNITQILDLFSYKLFWHGIHRVVL 436
            .:...|.||  .|.:..|..|       |..:.:       :|:..:::..:..:|      :..
 Worm   334 GTTEHEFRN--VDHMNPYISGIFLDFDNPVAVARYYDEQLMANLETMINGDAAAIF------ICA 390

  Fly   437 SRLSHAQAPT----YLYR-----FDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYI--FHKQAQA 490
            |..|.|.|.|    ||:.     :.|                      |..|:.|.  .|::...
 Worm   391 STFSTAMANTGADVYLFETRQKPYSF----------------------HVSDMQYFVGIHREIYH 433

  Fly   491 KQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGP-DP 527
            :..:|..:....:    :|..|.:.|.|: ||..| ||
 Worm   434 RPDMDILDTFYSK----LLVNFTKMGVPS-PEWAPLDP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	127/541 (23%)
		Aes	<133..325	CDD:223730	52/209 (25%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	127/535 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.830