Protein Alignment alpha-Est6 and glit-1

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 142/554 - (25%)
• Similarity: 215/554 - (38%)
• Gaps: 171/554 - (30%)

  Fly    39 DSKVVKLSVGSVKGRRL-------------------SGIYGD----------EFYSFEGIPFAKP 74
            |..||:|.:|.:.|:.:                   .|.:.|          ..::|.|:|:|:|
 Worm    53 DEVVVRLPLGDIVGKEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNITVFTFLGVPYAEP 117

  Fly    75 PLGKARFVASQ-----------LADPWNSELDARQ----------ERPIPLQMDRRSGKVVGSED 118
            |..:.||...|           ||  :|......|          :.|.|..:|         ||
 Worm   118 PTSQRRFKPPQQLTVFPGKQPYLA--FNYAASCAQDVEKSPSPFVDHPYPFMVD---------ED 171

  Fly   119 CLYLNVYTKHFNE-SEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFL 182
            |||||:::...:: ::...||:|:.:||.|:||.|  :::....|.||.:|.|..||||.:.||:
 Worm   172 CLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSA--NEWPAHGLASRGMVVVTVNYRLGAFGFM 234

  Fly   183 SMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFH 247
            ||...:   .||.||.||.|||::|..:|..|.||||.:|:.|..|||||:.|.|..|.::.||.
 Worm   235 SMGDSE---TGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFR 296

  Fly   248 KAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEV--------------PILEFLRNVNAE 298
            .|..|||:.:|.......:...|........|.|..:.|              .|::..||:..|
 Worm   297 SAATMSGAEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRNIPIE 361

  Fly   299 KLIGHDFISPRDRCFGFLNPFAPVVGG----------LVAAPFQQ--LMKEAWSCEVPLLLGGTS 351
                      .:|..     |.|.|.|          ||.||..:  :|.     .||:|:|..:
 Worm   362 ----------YNRYL-----FMPTVDGKYLPGNPLWTLVNAPSGETSIMS-----PVPMLIGMNA 406

  Fly   352 FEGLVYY-------PFCQLDNGYMLELLKHEPAMVLPHELYQSMSVE---------ERNTAAD-V 399
            .:|....       .|.|.::              :.||..:|.|:|         .|...|| :
 Worm   407 QDGSEVVLEDRRLGEFSQFND--------------VDHEYLKSYSLEYCYRHNYSMNREATADAI 457

  Fly   400 LVKYHYGP----RGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYL------YRFDFD 454
            |.||.:.|    ....|.|..|    |:...::..  .:.||...|:.:.:.:      |.|...
 Worm   458 LSKYTFWPDRAAAWAIKENFIQ----FATDAYYTA--PMQLSSHLHSSSGSRVFQYVNNYNFSRQ 516

  Fly   455 SPKLNLMRNQLCGDDIKRGVCHADDL----GYIF 484
            .|.|..:.:.:       |||...||    ||.|
 Worm   517 HPNLLFIPDWM-------GVCRDCDLYLMFGYPF 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	142/554 (26%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	134/509 (26%)