Protein Alignment alpha-Est6 and cest-26

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 598
• Identity: 170/598 - (28%)
• Similarity: 246/598 - (41%)
• Gaps: 134/598 - (22%)

  Fly    40 SKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPL 104
            ||.|:...|.|:|.|:......|...|.||||||.|:|..||...:..:.|:......:..|...
 Worm    41 SKQVRTRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAP 105

  Fly   105 QMD---RRSGKVVG-SEDCLYLNVYTKHFNESEPP---LPVMVYIYGGAFRTGGAVKSKYGPD-- 160
            |.|   .|....|| |||||||||::..:...|..   .|||||::||.|....||  |||.:
 Worm   106 QADFFWERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAV--KYGDEGI 168

  Fly   161 --YLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITL 223
              ||....||.|...|||..|||.|  :|....|||.||.|..:|||||..::..|.|||:.:|:
 Worm   169 AKYLCRHGVVVVTIQYRLGLLGFFS--TGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTV 231

  Fly   224 FGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW--------VNAPDSDGIFCRL------- 273
            ||:|||..||..:...|.::.|||:.:.|:|:....|        |||       ||.
 Worm   232 FGQSAGGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNA-------CREFAYRKCW 289

  Fly   274 -ATSAGYEGPAEEVPILEFLR---------------NVNAEKLIGHDFISPRDRCFGFLNPFAPV 322
             ...|..|..:|.  :|||||               .|:..| ||.|              .|||
 Worm   290 DEKQARDENASES--MLEFLRTRKEREFEKRLLTRKGVDVSK-IGLD--------------LAPV 337

  Fly   323 VGG----LVAAPFQQLMKEAWSCEVP---LLLGGTSFEGLVYYP-----FCQLDNGYMLELL--- 372
            :|.    .:....::|.|||     |   :::|....|||::..     |.:.....:|.||
 Worm   338 IGSKPSDFLPKSIEELRKEA-----PKKNIMVGTCEHEGLLFASLGPSNFDEKGIDKLLALLITE 397

  Fly   373 -KHEPAMVLPHELYQ------SMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHG 430
             .||....|..|..:      |...:::..||          ||        .:.|:|.....:|
 Worm   398 ENHEDFEALREEAKKMYLKKLSDDEDDKEVAA----------RG--------YIQLYSDLFVNNG 444

  Fly   431 IHRVVLSRLSHAQAPTYLYRFDFDSPK----LNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAK 491
            .:... .:::......::|.||:.:|:    |:|...       .|...|..:|.|||.......
 Worm   445 TYNYA-EKMTKLGNKVFMYSFDYCNPRSFGILSLRAP-------FRAATHCTELAYIFGVSIVFN 501

  Fly   492 QPLDSPEFLTIQRMVGILTTFARTGDPNC---PETGPD-PWMPVSTKSP--FKALNIGQQVECVT 550
            ...:..:...:..|..:.|.||:.|:||.   ..|..| .|.|.|.:.|  |.|:| .::.|..|
 Worm   502 YRYNESDRAMLDLMTKMWTNFAKYGNPNGQYEDSTVFDFKWEPTSKEEPTNFLAIN-EKKCEMQT 565

  Fly   551 QVEKDGLKVWNRL 563
            ..:.:..:.|.::
 Worm   566 VYQDNRAEFWKKI 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	163/567 (29%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	169/593 (28%)