Protein Alignment alpha-Est6 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 126/549 - (22%)
• Similarity: 209/549 - (38%)
• Gaps: 151/549 - (27%)

  Fly    43 VKLSVGSVKGRRLSGIY---GDEF-YSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIP 103
            |:||.|:::|:.|:..|   |:.. ..|.||||.:||.|..||...:...||:..|:.::.:|..
 Worm    21 VQLSTGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPAC 85

  Fly   104 LQMDRRSGK--VVG--SEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMS 164
            :...:::.|  |.|  ||||||.||:|..:........||:.::||...|..|  |.:.|:.|::
 Worm    86 MSDAKKTYKNGVGGPISEDCLYANVFTNQYCMKRKNCSVMIVVHGGRILTESA--SAFNPEILVN 148

  Fly   165 ------RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITL 223
                  |::|.|.|||||.:.||..:...|.|  .|.|:.|.|.|::|..:.:.||.|:...:|:
 Worm   149 NFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGD--SNVGMFDMLEAVKWTRKEVHNFGGNKDKLTM 211

  Fly   224 FGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPI 288
            .|.|||.:.|......|.:||:.::.|:|||::..           ..:||...|....|::...
 Worm   212 VGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGALYQ-----------MGKLANFKGMTAMAQKAGC 265

  Fly   289 L------------------EFLRNVNAEKLI--------------------GHDFISPRDRCF-- 313
            |                  ..|||::|::::                    |...::..|...
 Worm   266 LPEVFGFRKLSQVRIDKTYSCLRNISAQEVLDAQLWVLQNTTYYISVPHIDGEFLLNYSDEILAS 330

  Fly   314 GFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAM 378
            |.::|...::|...|           ....|:.:.             .|.|....|.|......
 Worm   331 GTIHPINSMIGTTTA-----------ELRDPIYIN-------------DLKNADKKEELLKNLCE 371

  Fly   379 VLPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQ 443
            .:.:|||.......|.      .:..|| .|.....:...::      |:.|..:|.   .:||.
 Worm   372 HIGYELYTEPEEFSRK------CQKFYG-NGDDAQFLADDME------FYDGSIKVA---NAHAS 420

  Fly   444 APT--YLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTI---- 502
            ..|  ::|.:|:                        .|.|..|.|.|||..|..|.:.:.:
 Worm   421 KNTKVFMYSYDY------------------------KDAGPAFKKYAQAPPPHHSEDLIYVFGTS 461

  Fly   503 ------------QRMVGILTTFARTGDPN 519
                        |...|:...|...|:|:
 Worm   462 RGNFTEKDYVIEQIYSGMFADFVNFGNPS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	126/549 (23%)
		Aes	<133..325	CDD:223730	56/237 (24%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	126/549 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740