Protein Alignment alpha-Est6 and cest-24

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 164/568 - (28%)
• Similarity: 247/568 - (43%)
• Gaps: 87/568 - (15%)

  Fly    30 FSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNS-- 92
            ||...:|.:::.:|::..|.::|.|:....||....|.|||:|:||:|:.||...|....|..
 Worm    85 FSNLKSGKSENAIVRVQQGLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAWEGIR 149

  Fly    93 ELDARQERPIPLQM--DRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVK- 154
            :.:....|.|..:|  |:.......|||||||||:.....| :...||:.||:||.:....|.:
 Worm   150 KCNKYPNRSIHKEMPWDKALPSANQSEDCLYLNVFAPKIRE-DKKYPVLFYIHGGGYVMDSAERY 213

  Fly   155 -SKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDP 218
             :|.....|:||:::.|.|:|||..|||||  :|....|||.||.|.|.|::||..:|.:|.|||
 Worm   214 TAKNICKLLVSREIIVVTFHYRLGFLGFLS--TGDDVCPGNYGLFDMLEAMRWVHANISSFGGDP 276

  Fly   219 QNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSD-GIFC-----RLA--T 275
            :||||.|:|||||:...:...|..||||.:.|:|.|:....|....:.| ..:|     ||.  .
 Worm   277 ENITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRLGWKP 341

  Fly   276 SAGYEGPAEE-VPILEFLRNVNAEKLIGHDFISPR--DRCFGFLNPFAPVVGGLVAAPFQQLMKE 337
            ...|....|| |.|..|...:...||....|.|..  ..|   ..|.|||:.|.:.....::::|
 Worm   342 QLNYANKREESVDIFNFFNGLPTSKLGMTMFFSNTIFKEC---QLPLAPVIDGEILPHDLKVLRE 403

  Fly   338 AWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVK 402
            ... .||.|:||..:|.|:   ||.:.      ||:.              :.:|.|:|.|||.:
 Worm   404 TQE-HVPSLVGGGEYEALL---FCAIG------LLRG--------------TEKEINSAIDVLSR 444

  Fly   403 YH--------------YGP----RGITKSN----ITQILDLFSYKLFWHGIHRVVLSRLSHAQAP 445
            .:              ||.    |..:|:.    :..|.|:|:.    :|.:| .:.........
 Worm   445 KNRLSRSKIEAMTEKVYGDSPALRADSKARKMFFVQLISDIFAN----YGNYR-FMRDCQQRGVE 504

  Fly   446 TYLYRFDFDSPKLNLMRNQLCG--DDIK--RGVCHADDLGYIFH-KQAQAKQPLDSPEFLTIQRM 505
            .|.|.||..|       .|:.|  ..:.  .|..|..:|.|:|. ....|...::..:.:.....
 Worm   505 CYGYSFDHQS-------KQMWGWLQHVVPFTGGTHTSELSYLFDCNYMSAPLGMNKTDKVVSGMT 562

  Fly   506 VGILTTFARTGDPNCPETGPDPWMPVSTKSP-FKALNIGQQVECVTQV 552
            ....|.|.:.|.||.|.:....|..:|.... .|.::|..:.|..|.|
 Worm   563 ADYFTNFVKFGTPNGPNSQLPKWERISPDDEHMKLISIKPEPEMKTTV 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	156/540 (29%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	159/552 (29%)