Protein Alignment alpha-Est6 and cest-35.1

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 598
• Identity: 165/598 - (27%)
• Similarity: 251/598 - (41%)
• Gaps: 135/598 - (22%)

  Fly    39 DSKVVKLSVGSVKGRRLSGIY--GDEFY-SFEGIPFAKPPLGKARFVASQLADPWNSELDARQER 100
            :::|:..|.|.::|    .||  .|:.. .:.||||||.|:|:.||..|..|:.|...||..:..
 Worm    13 NTEVLNASCGPIRG----NIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYG 73

  Fly   101 PIPLQMDRRSGKVV---------GSEDCLYLNVYTKHFNESEPP--LPVMVYIYGGAFRTGGAVK 154
            |...|.......:|         ..::||.|||:...:..:|.|  |||:||.|||.|..|   .
 Worm    74 PGCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEVG---F 135

  Fly   155 SKYGPDYLMS-----RDVVYVLFNYRLCSLGFLSMPSGKLDVP-GNAGLHDQLLALQWVSQHIRN 213
            |....||.::     :||:.|..|||:..|||.:...   ||. ||.||.||.||||||.:||::
 Worm   136 SSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGD---DVSRGNWGLWDQALALQWVQKHIKS 197

  Fly   214 FNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPDSDG-IFCRLATS 276
            |.|||.|:|:.|.|||.|||.|:...|.|...|||.|.|||:...|: :.:.|.:| ||...|..
 Worm   198 FGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRSKDVEGLIFREFAKH 262

  Fly   277 AGYEGPAEEVPILEFLRNVNAEKLI-GHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWS 340
            .||.|...| .:|.:.::.:||..: ...|..|....|.|:..:.   |.....||.:|.|||
 Worm   263 HGYAGNDSE-SLLHWYQSQDAEIFLKAEGFKYPASGMFSFVPNYD---GDFFPKPFDELRKEA-- 321

  Fly   341 CEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHY 405
            .::..::....:|||.:..|              .|....|.|:.         |||       .
 Worm   322 PKLDAIVSVAEYEGLGFEEF--------------YPGQKSPQEVL---------TAA-------L 356

  Fly   406 GPRGITK-------------SNI---------TQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYL 448
            ||..:..             .||         .:::::|....|..|:...|.|...:.. ..||
 Worm   357 GPEVVRNREEVVKKAVEAYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGN-NVYL 420

  Fly   449 YRFDFDSPKLNLMRNQLCGDDIK-RGVCHADDLGYI-------FHKQAQAKQPLDSPEFLTIQRM 505
            ..|::.:|:..:|    .|::.. ....|..|:.||       |.|:.:           .:..|
 Worm   421 SSFNYFNPETPIM----FGENRPFNAASHGCDIRYILGDGIGEFSKEDR-----------KVMDM 470

  Fly   506 VG-ILTTFARTGDPNCPETGPD---PWMPVSTKSPFKALNIGQ------------QVECVTQVEK 554
            :| .||.||:.|:||    |..   ||...|..:|.:...|..            :.:.:.:|.:
 Worm   471 MGTYLTNFAKYGNPN----GKGVSIPWEKYSLDNPGRYFKIDYPKCEMADNFLDGRYKIIDEVNE 531

  Fly   555 DGLKVWNRLYSDL 567
            .|::....::..:
 Worm   532 HGIQYQEMVFGKI 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	161/553 (29%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	163/572 (28%)