Protein Alignment alpha-Est6 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 162/539 - (30%)
• Similarity: 246/539 - (45%)
• Gaps: 76/539 - (14%)

  Fly    37 DADSKVVKLSVGSVKGRRLSGIY--GDEFYS-FEGIPFAKPPLGKARFVASQLADPWNSELDARQ 98
            :.:::|...|.|.::|    .:|  ||:..: :.||||||.|:|..||..|..|:.|...||..:
 Worm    11 EKNTEVFNASCGPIRG----NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYK 71

  Fly    99 ERP-IP-------LQMDRRSGKVVGSEDCLYLNVYTKHFNESEPP--LPVMVYIYGGAFRTGGAV 153
            ..| .|       |.:.:.:......::||.|||:...:..:|.|  .|||||.|||.|..|
 Worm    72 YGPGCPQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVG--- 133

  Fly   154 KSKYGPDYLMS-----RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRN 213
            .|....||.::     :||:.|..|||:..|||.:  :|.....||.||.||.||||||.:||::
 Worm   134 FSSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFA--TGDDVARGNWGLWDQALALQWVQKHIKS 196

  Fly   214 FNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPDSDG-IFCRLATS 276
            |.|||.|:|:.|.|||.|||.|:...|.|...|.|.|.|||:...|: :.:.|.:| ||...|..
 Worm   197 FGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANH 261

  Fly   277 AGYEGPAEEVPILEFLRNVNAEKLI-GHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWS 340
            .||.| .:...:|::.::.::|..: ...:..|....|.|:..|.   |.....||.:|.|||..
 Worm   262 HGYTG-NDSKSLLQWYQSQDSEIFLKAEGYKCPASGMFSFVPNFD---GDFFPKPFDELRKEAPK 322

  Fly   341 CEVPLLLGGTSFEGLVYYPFC--QLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKY 403
            ....:.:|  .:|||.:..|.  |.....||.      |.:.|..:.....|.:|  ||:..:|.
 Worm   323 LGAIVSIG--EYEGLGFEDFYAGQKTPQQMLS------AALGPEVVRNREEVVKR--AAESYLKN 377

  Fly   404 --HYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNLM--RNQ 464
              :.....|.|:    ::::|....|..|....|.|.:.:... .|||.|::.:|...::  :|:
 Worm   378 GGNENEENIAKT----LVEIFGDYYFSVGAFDTVRSLVKYGNT-VYLYSFNYFNPNTPIVFGKNR 437

  Fly   465 LCGDDIKRGVCHADDLGYIFHK-----QAQAKQPLDSPEFLTIQRMVGIL-TTFARTGDPNCPET 523
            ..     ....|..||.|||.:     ..:.:|.:|         |:|.. |.||:.|:||....
 Worm   438 PF-----NAANHGSDLRYIFGEGTGEFSKEDRQVMD---------MMGTYHTNFAKYGNPNGKGV 488

  Fly   524 GPDPWMPVSTKSPFKALNI 542
            .. ||...|..:|.:...|
 Worm   489 SV-PWEKYSLDNPGRYFKI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	160/529 (30%)
		Aes	<133..325	CDD:223730	76/201 (38%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	162/536 (30%)
		Aes	<105..>239	CDD:223730	62/138 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157291
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750