Protein Alignment alpha-Est6 and cest-32

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 153/576 - (26%)
• Similarity: 241/576 - (41%)
• Gaps: 102/576 - (17%)

  Fly    37 DADSKVVKLSVGSVKGRRLSGIY--GDEFYS-FEGIPFAKPPLGKARFVASQLADPWNSELDARQ 98
            :|..:|:..|.|.|.|    .||  .|:..: :.||||||.|:.:.||.....|:.|...|:..:
 Worm    11 EASLEVLNASCGPVIG----NIYRHDDKIVNGYLGIPFAKAPICELRFKKPVEAEKWTKPLNCHK 71

  Fly    99 ERP-IPLQMDRRSGKVVGS-----------EDCLYLNVYTKHFNESEPP--LPVMVYIYGGAFRT 149
            ..| .|     :||.::.:           ::||.||::...:...|.|  ||:|||.:||.|..
 Worm    72 YGPGCP-----QSGHMISNLLPPGYREFAEDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEI 131

  Fly   150 GGAVKSKYGPDYLMS-----RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQ 209
            |   .|....||.:|     :||:.|..|||:..|||  |.:|.....||.||.||.|||:||.:
 Worm   132 G---FSSMFDDYSLSGTLPLKDVIVVTANYRVGPLGF--MTTGDEVSRGNYGLWDQTLALKWVQE 191

  Fly   210 HIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPDSDG-IFCR 272
            ||::|.|:|..:|:.|.|||..|...:...|.:..|||:.:.||||....: :...:.:. ||..
 Worm   192 HIKSFGGNPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRN 256

  Fly   273 LATSAGYEGPAEE--------VPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAA 329
            .|...||||...|        .|:.:|......||           :..|||.......|.....
 Worm   257 FAKHHGYEGEDSESLLEWYKSQPLSKFQETATFEK-----------KASGFLTFIPNFDGDFFPK 310

  Fly   330 PFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERN 394
            ||.:|.:||...:....:  ..:|||.:....|.....| :::|            .|...:...
 Worm   311 PFDELSREAPKLDAMATV--DEYEGLGFLTMFQSRRNDM-DIIK------------SSFGSDVVE 360

  Fly   395 TAADV---LVKYHYGPRGITKSN----ITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFD 452
            .|.||   :::::.  :.|.|::    ..:::.|.|...|..|....|.:...:. :..||..||
 Worm   361 NAVDVQKRIMEFYM--KNIDKNDDKAVEKRLIQLISDSWFNIGALETVKTSTKYG-SNAYLGSFD 422

  Fly   453 FDSPKLNLMRNQLCGDDIK-----RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTF 512
            :    .|:..|    |...     :...|..:|.|:..:......|::. ||..|..|..:...|
 Worm   423 Y----YNMGSN----DPYATWFPFKAANHGSELKYMLGEGMGKFSPIEE-EFKVIDMMGTLTANF 478

  Fly   513 ARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDG-LKVWNRLYSDL 567
            .:.|:|| ...||:.|...:.:.|:....|......:....:|| ||    |:.|:
 Worm   479 VKYGNPN-GINGPELWKKYTPEKPYSYFKIDYPKSEMRDNFQDGRLK----LFEDI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	145/540 (27%)
		Aes	<133..325	CDD:223730	71/208 (34%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	146/553 (26%)
		Aes	<104..>227	CDD:223730	49/127 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740