Protein Alignment alpha-Est6 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 133/532 - (25%)
• Similarity: 208/532 - (39%)
• Gaps: 150/532 - (28%)

  Fly    41 KVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQ 105
            :::|.|:|.::|:: ||    ::..|..|||||||:|..||...:.|:.||...:|.:..|..:.
 Worm    22 RIIKTSLGRLEGKQ-SG----KYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMS 81

  Fly   106 MD--RRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLM----S 164
            ..  .:|.:....||||::|::|...........|:|||:||......||  .:...:|:    .
 Worm    82 NSTWTQSPQKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAV--MFNDTFLLESFVK 144

  Fly   165 RDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAG 229
            :||:.|:..:||......::....: .|.|..|:|.:||.::|...|.||.||.|.|||||.|.|
 Worm   145 QDVILVIPAFRLGIFSHFTVHDQNI-APNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYG 208

  Fly   230 ---AASVHFMMCLPQAKGLFHKAIMMSGSM----LSPWVNAPDSDGIFCRLATSAGYEGPAEEVP 287
               |:.:.|...:.|...||.:.|:||.:.    |...:...|      |:...||...|.
 Worm   209 GTIASMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIERSD------RVVKHAGCSVPT---- 263

  Fly   288 ILEFLRNVN-----------AEKLIGHDFISPRDRC--FGFLNPFAPVVGGLV-AAPFQQLMKEA 338
              ...|.:|           .:||.|.:.:|.:...  .|:     |.:|.|| ..|   |..:.
 Worm   264 --NLARKMNRSQKEKYMMKCLQKLSGMELLSVQRSLEEAGY-----PDIGNLVLRGP---LFPDV 318

  Fly   339 WSCE-------VPLLLGGTSFE--------------GLVYYPFCQLDNGYMLELLKHEPAMVLPH 382
            .|.|       :|:|.|.|.||              ||.....|  |..|..:         |.:
 Worm   319 TSLEMLESPKMIPMLAGCTKFESDDEDETHFIGKHFGLENPIEC--DEKYRKD---------LEN 372

  Fly   383 ELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTY 447
            .::...:..::..|  ::|.        ||..:.|:..        ||:             |.|
 Worm   373 GIFDRQNHSDKTQA--IMVP--------TKLRVDQLRK--------HGV-------------PAY 406

  Fly   448 LYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYI-----FHKQAQAKQPLDSPEFL-TIQRMV 506
            ||.|.:  ||               ...|.|||.||     |.|.       ::.|.| .:.|
 Worm   407 LYEFTY--PK---------------HAFHTDDLYYIMGIHPFEKD-------ENEEHLEKVYR-- 445

  Fly   507 GILTTFARTGDP 518
            .:|..|.:.|:|
 Worm   446 NMLINFIKFGEP 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	133/532 (25%)
		Aes	<133..325	CDD:223730	56/215 (26%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	133/531 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830