Protein Alignment alpha-Est6 and ace-3

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_496963.1
• Gene: ace-3 / 175076
• WormBaseID: WBGene00000037
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 169/622 - (27%)
• Similarity: 257/622 - (41%)
• Gaps: 146/622 - (23%)

  Fly    10 RSRIKCFRFLILRCCPGFKRFSCQSAGDADSKVVKL--SVGSVKGRRLSGIYGDE-FYSFEGIPF 71
            |.|:    .|:|.....|.|.|.....:..:.||::  .:|:|:|....  :|:: ..||.|:||
 Worm     3 RRRV----LLLLLSTTTFLRVSTAQQDEPKASVVEVQTKLGTVRGTESD--HGNKRVRSFLGVPF 61

  Fly    72 AKPPLGKARFVASQLADPWNSELDARQERPIPLQ-----------MDRRSGKVVGSEDCLYLNVY 125
            |:||:.:.||.....|.|||..:.|....|...|           .:..:.....||||||:|::
 Worm    62 AEPPINEHRFKKPTPARPWNGTISANTLSPACFQGRDSYDPTFWGSEMWNANTPVSEDCLYVNIW 126

  Fly   126 --TKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSR-DVVYVLFNYRLCSLGFLSMPSG 187
              ...:|     |.|:|:::||.|..|......|....|.:| :|:.|..|||:...|:|.:...
 Worm   127 APADAYN-----LTVLVWLFGGGFWYGSPSLLLYDGKELATRGNVIVVNINYRVGPFGYLFLDHE 186

  Fly   188 KLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMM 252
              |||||.|:.||.|||.|:..||.:|.|:|..|:|.||||||||:...:..|.:||||...|:.
 Worm   187 --DVPGNMGMLDQQLALYWIRDHIFSFGGNPARISLVGESAGAASIVAHLIAPASKGLFQNGILQ 249

  Fly   253 SGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILE---FLRNVNAEKLI------GHDFISP 308
            |||:.:.|  :.||.....:.:|:........:..|.:   .|||..|:.||      |.:|:.
 Worm   250 SGSLDNKW--SMDSPKRAKQKSTALADLVGCNQTKITDQTACLRNTPAQLLIDNIWNVGLNFLE- 311

  Fly   309 RDRCFGFLNPFAPV---------VGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLD 364
                    .|||.|         :.|.:|     |.:..:|.:|.|:.|....||..:
 Worm   312 --------FPFAIVSKDQNFFKHLDGFIA-----LREGTYSTDVNLMFGINHDEGNFW------- 356

  Fly   365 NGYMLELLKHEPAMVLP-------HELYQ---SMSVEERNTAADVLVKYHYG------PRGITKS 413
            |.|.|... .:...|.|       ||...   ::..|...|||    ||.|.      |:..|..
 Worm   357 NIYNLAKF-FDKQSVKPGLDRDEFHECVDTAFAVQPELVRTAA----KYVYSDPKCTDPKKKTDF 416

  Fly   414 NITQILDL-----FSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDS-----PKLNLMRNQLCGD 468
            ...|:..:     |:....|.. |.  ..:::..|:..::|.||..|     ||..
 Worm   417 YTEQVNQMVGDYFFTCDSIWFA-HN--YPKMAGNQSNVFVYYFDQPSSANPWPKWT--------- 469

  Fly   469 DIKRGVCHADDLGYIF----HK--QAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPE----- 522
                ||.|..::.|:|    |.  ....|:.:|..|     :::...||||.||.|:..:
 Worm   470 ----GVMHGYEIEYVFGVPLHNTTAGYTKEEMDVSE-----KVIDFWTTFANTGVPSLRKRAVGT 525

  Fly   523 -----------TGPDPWMPVSTKSPFKALNIGQQVEC 548
                       |....||.:.|.| |:.:...::|||
 Worm   526 TQKIKWDRYDGTDHTTWMNIKTGS-FRMIQEIKKVEC 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	157/579 (27%)
ace-3	NP_496963.1	COesterase	33..564	CDD:395084	160/588 (27%)