Protein Alignment alpha-Est6 and cest-27

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 165/599 - (27%)
• Similarity: 260/599 - (43%)
• Gaps: 110/599 - (18%)

  Fly    17 RFLILRCCPGF--KRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKA 79
            |||:    .||  |.....:..||       :.|.:||.......|.....|.|||:|:||:|..
 Worm    11 RFLM----GGFLSKHHHLTAVHDA-------TCGPIKGVGYEQEDGSVVEGFLGIPYAEPPIGAL 64

  Fly    80 RFVASQLADPWNSELDARQERPIPLQMDRRSGKVVGS-----EDCLYLNVYTKHFNESEPP--LP 137
            ||........|...||..:..|...|.|...|:.|.:     |.||.|||:|..:..:|.|  .|
 Worm    65 RFKKPVAHRKWTEPLDCVRFGPRSPQNDELLGQFVNTVGKSEEHCLSLNVFTPKWESNEWPDGFP 129

  Fly   138 VMVYIYGGAFRTGGAVKSKYG----PDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLH 198
            |||:|:||.|....:  |.||    ...|.::|||.|..||||..|||.:  :|.....||.||.
 Worm   130 VMVFIHGGGFAVHSS--SNYGCASIARNLCTKDVVVVTINYRLGVLGFFT--TGDEVCRGNLGLW 190

  Fly   199 DQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VN 262
            ||..||:||.::|::|.|||.|:|:||:|||.|||..:...|.::|||::||.|:|:....: :.
 Worm   191 DQTAALEWVQENIQSFRGDPDNVTIFGQSAGGASVDLLCLSPHSRGLFNRAIPMAGNGECDFAMR 255

  Fly   263 APDSDGIFCR-LATSAGYEGP----------AEEVPILEFLRNVNAEKLIGHD------FISPRD 310
            ..:......| .|...|:||.          .::.|:.:....:|.::...|.      |:...|
 Worm   256 TSEQQAQLSREFARYLGWEGDDNDSEDLLQFIDQQPLYKIEMGINPKRGFKHSQAGSLYFVPNFD 320

  Fly   311 RCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHE 375
                         |.....|..||.|||  .::.::.|.|.:|||.:         ..|..|...
 Worm   321 -------------GDFFPKPLNQLRKEA--PKMQIMTGTTKYEGLFF---------IALGALSKN 361

  Fly   376 PAMV--LPHELYQSMSVEERNTAADVL-VKYHYGPRGI----TKSNITQILDLFSYKLFWHGIHR 433
            |..:  ....:::.....||  |.||| :.|.:..:|:    .:.|:.||:.........:|.:|
 Worm   362 PEGIKKFMGRIFKECDYGER--ADDVLQMVYDFYFKGVHPKDHEKNMHQIVKFIGDYSINYGTYR 424

  Fly   434 V--VLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDDIKR------GVCHADDLGYIFHKQAQA 490
            :  :::.|.|   ..|.|:||:         :...|..:.|      |..|..::.|:..|...:
 Worm   425 LANIMTDLQH---DVYFYQFDY---------HNSAGFGVFRWLLPFLGSTHCTEMRYVLGKGIIS 477

  Fly   491 K-QPLDSPEFLTIQRMVGILTT----FARTGDPNCPETGPDPWMPVSTKSPFKALNIG-QQVECV 549
            | :|.|:.     ::|:.::||    ||:.|:||........|....:..||:...|. ...|.|
 Worm   478 KFRPNDND-----KKMLHVMTTYFTNFAKYGNPNGENQETGEWQKHDSAHPFRHFKIDLDDSEMV 537

  Fly   550 TQVEKDGLKVWNRL 563
            ...::...::|::|
 Worm   538 EDYQERRAELWDKL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	150/545 (28%)
cest-27	NP_871861.2	COesterase	29..548	CDD:395084	157/572 (27%)