Protein Alignment alpha-Est6 and cest-27

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 165/599 - (27%)
• Similarity: 260/599 - (43%)
• Gaps: 110/599 - (18%)

  Fly    17 RFLILRCCPGF--KRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKA 79
            |||:    .||  |.....:..||       :.|.:||.......|.....|.|||:|:||:|..
 Worm    11 RFLM----GGFLSKHHHLTAVHDA-------TCGPIKGVGYEQEDGSVVEGFLGIPYAEPPIGAL 64

  Fly    80 RFVASQLADPWNSELDARQERPIPLQMDRRSGKVVGS-----EDCLYLNVYTKHFNESEPP--LP 137
            ||........|...||..:..|...|.|...|:.|.:     |.||.|||:|..:..:|.|  .|
 Worm    65 RFKKPVAHRKWTEPLDCVRFGPRSPQNDELLGQFVNTVGKSEEHCLSLNVFTPKWESNEWPDGFP 129

  Fly   138 VMVYIYGGAFRTGGAVKSKYG----PDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLH 198
            |||:|:||.|....:  |.||    ...|.::|||.|..||||..|||.:  :|.....||.||.
 Worm   130 VMVFIHGGGFAVHSS--SNYGCASIARNLCTKDVVVVTINYRLGVLGFFT--TGDEVCRGNLGLW 190

  Fly   199 DQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VN 262
            ||..||:||.::|::|.|||.|:|:||:|||.|||..:...|.::|||::||.|:|:....: :.
 Worm   191 DQTAALEWVQENIQSFRGDPDNVTIFGQSAGGASVDLLCLSPHSRGLFNRAIPMAGNGECDFAMR 255

  Fly   263 APDSDGIFCR-LATSAGYEGP----------AEEVPILEFLRNVNAEKLIGHD------FISPRD 310
            ..:......| .|...|:||.          .::.|:.:....:|.::...|.      |:...|
 Worm   256 TSEQQAQLSREFARYLGWEGDDNDSEDLLQFIDQQPLYKIEMGINPKRGFKHSQAGSLYFVPNFD 320

  Fly   311 RCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHE 375
                         |.....|..||.|||  .::.::.|.|.:|||.:         ..|..|...
 Worm   321 -------------GDFFPKPLNQLRKEA--PKMQIMTGTTKYEGLFF---------IALGALSKN 361

  Fly   376 PAMV--LPHELYQSMSVEERNTAADVL-VKYHYGPRGI----TKSNITQILDLFSYKLFWHGIHR 433
            |..:  ....:::.....||  |.||| :.|.:..:|:    .:.|:.||:.........:|.:|
 Worm   362 PEGIKKFMGRIFKECDYGER--ADDVLQMVYDFYFKGVHPKDHEKNMHQIVKFIGDYSINYGTYR 424

  Fly   434 V--VLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDDIKR------GVCHADDLGYIFHKQAQA 490
            :  :::.|.|   ..|.|:||:         :...|..:.|      |..|..::.|:..|...:
 Worm   425 LANIMTDLQH---DVYFYQFDY---------HNSAGFGVFRWLLPFLGSTHCTEMRYVLGKGIIS 477

  Fly   491 K-QPLDSPEFLTIQRMVGILTT----FARTGDPNCPETGPDPWMPVSTKSPFKALNIG-QQVECV 549
            | :|.|:.     ::|:.::||    ||:.|:||........|....:..||:...|. ...|.|
 Worm   478 KFRPNDND-----KKMLHVMTTYFTNFAKYGNPNGENQETGEWQKHDSAHPFRHFKIDLDDSEMV 537

  Fly   550 TQVEKDGLKVWNRL 563
            ...::...::|::|
 Worm   538 EDYQERRAELWDKL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	152/547 (28%)
		Aes	<133..325	CDD:223730	69/215 (32%)
cest-27	NP_871861.2	COesterase	29..541	CDD:278561	157/565 (28%)
		Aes	<114..>283	CDD:223730	66/172 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850