Protein Alignment alpha-Est6 and Ces1e

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 599
• Identity: 177/599 - (29%)
• Similarity: 265/599 - (44%)
• Gaps: 101/599 - (16%)

  Fly    15 CFRFLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYS-----FEGIPFAKP 74
            |...|||.....|    ...||...|..:   |.:|:|:.|......|.::     |.|:|||||
Mouse     2 CLSALILVSLAAF----TAGAGHPSSPPM---VDTVQGKVLGKYISLEGFTQPVAVFLGVPFAKP 59

  Fly    75 PLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVG--------------SEDCLYLNVY 125
            |||..||...|.|:||:|..:|....|:..| |..:|::|.              ||||||||:|
Mouse    60 PLGSLRFAPPQPAEPWSSVKNATSYPPMCFQ-DPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIY 123

  Fly   126 TKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRD-VVYVLFNYRLCSLGFLSMPSGKL 189
            |.........|||||:|:||....|||  |.|....|.:.: ||.|:..|||...||.|  :|..
Mouse   124 TPADLTKSDRLPVMVWIHGGGLVLGGA--STYDGLVLSTHENVVVVVIQYRLGIWGFFS--TGDE 184

  Fly   190 DVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSG 254
            ...||.|..||:.||.||..:|..|.|||.::|:||||||..||..::..|.||.||.:||..||
Mouse   185 HSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESG 249

  Fly   255 SMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLN-- 317
            ..|:..:...::..:..::|..:|.:. .....::..||....|:|:|...         .||
Mouse   250 VALTAGLVKKNTRPLAEKIAVISGCKN-TTSAAMVHCLRQKTEEELLGTTL---------KLNLF 304

  Fly   318 ------------PFAPVV--GGLVAAPFQQLMKEAWSCEVPLLLG------GTSFEGLVYYP--F 360
                        ||.|.|  |.|:....::::.|.....||.::|      |.....::.||  .
Mouse   305 KLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGINKQEFGWILPTMMNYPPSD 369

  Fly   361 CQLDNGYMLELLKHEPAMV-LPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSY 424
            .:||....:.|||....:: ||.:            |..|.::.:...:..|..|..|:|:|...
Mouse   370 VKLDQMTAMSLLKKSSFLLNLPED------------AIAVAIEKYLRDKDYTGRNKDQLLELIGD 422

  Fly   425 KLFWHGIHRVVLSRLSH--AQAPTYLYRFDFDSPKLN--LMRNQLCGDDIKRGVCHADDLGYIFH 485
            .:|  |:..|::|| .|  |.||||:|.|.: ||..:  :..:.:.||       |.|::..:|
Mouse   423 VVF--GVPSVIVSR-GHRDAGAPTYMYEFQY-SPSFSSEMKPDTVVGD-------HGDEIYSVF- 475

  Fly   486 KQAQAKQPLDSPEFLTIQR-MVGILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECV 549
             .|...:...|.|.:.:.: |:.....|||.|:||  ..|...|.....|..:  |.||...:..
Mouse   476 -GAPILRGGTSEEEINLSKMMMKFWANFARNGNPN--GQGLPHWPEYDQKEGY--LQIGATTQQA 535

  Fly   550 TQVEKDGLKVWNRL 563
            .::::..:..|..|
Mouse   536 QKLKEKEVAFWTEL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	166/548 (30%)
		Aes	<133..325	CDD:223730	70/208 (34%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	167/567 (29%)
		Aes	44..>242	CDD:223730	84/202 (42%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832958
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750