Protein Alignment alpha-Est6 and Ces1d

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 591
• Identity: 186/591 - (31%)
• Similarity: 264/591 - (44%)
• Gaps: 113/591 - (19%)

  Fly    31 SCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYS-----FEGIPFAKPPLGKARFVASQLADPW 90
            :|.:.|...|..|   |.:|||:.|......|.::     |.|:||||||||..||...|.|:||
Mouse    13 ACTAWGYPSSPPV---VNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPW 74

  Fly    91 N----------------------SELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESE 133
            :                      |||...::..||||.         ||||||||:||.......
Mouse    75 SFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQF---------SEDCLYLNIYTPADLTKN 130

  Fly   134 PPLPVMVYIYGGAFRTGGAVKSKY-GPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGL 197
            ..|||||:|:||....|||  |.| |.......:||.|...|||...||.|  :|.....||.|.
Mouse   131 SRLPVMVWIHGGGLVVGGA--STYDGLALSAHENVVVVTIQYRLGIWGFFS--TGDEHSRGNWGH 191

  Fly   198 HDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVN 262
            .||:.||:||..:|.||.|:|.::|:||||||..||..::..|.||.|||:||..||..|:..:.
Mouse   192 LDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALI 256

  Fly   263 APDSDGIFCRLATSAGYEGPAEEV-----------PILEFLRNVNAEKLIGHDFI-SPRDRCFGF 315
            ..|...|...:||.:|.:.....|           .:||....:|..||   |.: :|::.
Mouse   257 TTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKL---DLLGNPKES---- 314

  Fly   316 LNPFAP-VVGGLV--AAPFQQLMKEAWSCEVPLLLG------GTSFEGLVYYPFCQLDNGYMLEL 371
             .||.| |:.|:|  .||.:.|.::::| .||.::|      |.....|:.||..:       ..
Mouse   315 -YPFLPTVIDGVVLPKAPEEILAEKSFS-TVPYIVGINKQEFGWIIPTLMGYPLAE-------GK 370

  Fly   372 LKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYGPRGIT-KSNITQILDLFSYKLFWHGIHRVV 435
            |..:.|..|..:.|.::.:.| |....|..||..|...:| |.::.|  ||.:..:|  |:..|:
Mouse   371 LDQKTANSLLWKSYPTLKISE-NMIPVVAEKYLGGTDDLTKKKDLFQ--DLMADVVF--GVPSVI 430

  Fly   436 LSRLSH--AQAPTYLYRFDFDSPKLNLMR-NQLCGDDIKRGVCHADDL----GYIFHKQAQAKQP 493
            :|| ||  |.|.||:|.|::....::.|| ..:.||       |.|::    |..|.|...
Mouse   431 VSR-SHRDAGASTYMYEFEYRPSFVSAMRPKAVIGD-------HGDEIFSVFGSPFLKDGA---- 483

  Fly   494 LDSPEFLTIQRMV-GILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGL 557
              |.|...:.:|| .....|||.|:||  ..|...|.....|..:  |.||...:...:::...:
Mouse   484 --SEEETNLSKMVMKFWANFARNGNPN--GGGLPHWPEYDQKEGY--LKIGASTQAAQRLKDKEV 542

  Fly   558 KVWNRL 563
            ..|..|
Mouse   543 SFWAEL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	179/556 (32%)
		Aes	<133..325	CDD:223730	75/205 (37%)
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	181/575 (31%)
		Aes	<121..>239	CDD:223730	52/121 (43%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750