Protein Alignment alpha-Est6 and Ces2a

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 552
• Identity: 154/552 - (27%)
• Similarity: 238/552 - (43%)
• Gaps: 88/552 - (15%)

  Fly    13 IKCFRFLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRL------SGIYGDEFYSFEGIPF 71
            :.|...|:|:...|         .|:.|.:.....|.|:|..:      ||:     ::|.||||
Mouse    13 VACGLLLLLQHVHG---------QDSASPIRNTHRGQVRGSFVHVKDTKSGV-----HAFLGIPF 63

  Fly    72 AKPPLGKARFVASQLADPWNSELDARQERPIPLQ---MDRRSGKVVG--------SEDCLYLNVY 125
            ||||:|..||...:..:||:...|...:..:.||   |:....|.:.        ||||||||:|
Mouse    64 AKPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDIMNLEDAKEMNLILPPISMSEDCLYLNIY 128

  Fly   126 TKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLD 190
            |....:....|||||:|:||....|.|..:... ....:.::|.|...|||..|||.|  :|...
Mouse   129 TPTHAQEGSNLPVMVWIHGGGLVVGSASMNDVS-KLAATEEIVIVAIQYRLGVLGFFS--TGDQH 190

  Fly   191 VPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGS 255
            ..||.|..||:.||:||.::|..|.|:...:|:||.|||..||...:..|.:|||||.|||.||.
Mouse   191 ARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGV 255

  Fly   256 MLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFA 320
            .|.|.:.:..|:.::..:|..:|.|....|. ::..||..:.::::.             :|...
Mouse   256 ALLPDLISDTSEVVYKTVANLSGCEATDSEA-LIHCLRAKSKQEILA-------------INQVF 306

  Fly   321 PVVGGLVAAPF-----QQLMKEAWSCEVPLLLGGTSFE-GLVYYPFCQLDNGYMLELLKHEPAMV 379
            .::..:|...|     |:|:.......||.::|..:.| |.....|..||:     ::|:.....
Mouse   307 KMIPAVVDGEFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDH-----IIKNITRET 366

  Fly   380 LPHELYQSMSVEERNTAA---------DVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVV 435
            ||..|        :||||         .:||:.:.|.....::...|..::....:|  .|..:.
Mouse   367 LPAVL--------KNTAARMMLPPECSHLLVEEYMGDTEDPETLQAQFREMLGDFMF--VIPALQ 421

  Fly   436 LSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQA-QAKQPLDSPEF 499
            ::....:|||.|.|.|...|..:..:|......|      |.||:.::|.... .....|...|.
Mouse   422 VAHFQRSQAPVYFYEFQHLSSFIKHVRPSHVKAD------HGDDVAFVFGSYLWDMNLDLTEEEE 480

  Fly   500 LTIQRMVGILTTFARTGDPNCPETGPDPWMPV 531
            |..:.|:.....|||.|:||  ..|...| ||
Mouse   481 LLKRMMMKYWANFARNGNPN--SEGLPSW-PV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	150/530 (28%)
		Aes	<133..325	CDD:223730	61/191 (32%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	149/526 (28%)
		Aes	<127..>230	CDD:223730	39/105 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740