Protein Alignment alpha-Est6 and ces2.2

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_004913616.1
• Gene: ces2.2 / 100493994
• XenbaseID: XB-GENE-29081995
• Length: 568
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 180/621 - (28%)
• Similarity: 260/621 - (41%)
• Gaps: 151/621 - (24%)

  Fly    12 RIKCFRF-----LILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEF-YSFEGIP 70
            |.:|.:.     |:|.||...:.:..:.|    ..::....|.:.|..:.....|.. :.|.|:|
 Frog     6 RAECLQMGSLIKLLLLCCATLEIYGTEDA----RPLLTTKYGQLLGNTVGAKETDRLVHVFMGVP 66

  Fly    71 FAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVG------------SEDCLYLN 123
            |||||:|..||.|.|..:||:|..:|....|:.|| |:|..:.:.            ||||||||
 Frog    67 FAKPPIGPLRFEAPQPPEPWSSVREATAAPPMCLQ-DKRGMEDLAEFFKAKFDFPPVSEDCLYLN 130

  Fly   124 VYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGK 188
            |:|.......|.|||||:|:|||...|||...: |.......:||.|...|||..:||.|  ||.
 Frog   131 VFTPADRGENPELPVMVFIHGGALTMGGASMFE-GSALCAYENVVVVSIQYRLGIMGFFS--SGD 192

  Fly   189 LDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMS 253
            .:|.||.|..||:.|||||..:|::|.|:||::|:||||||..||...:..|.:||||||||..|
 Frog   193 KEVRGNFGFLDQVAALQWVRDNIKDFGGNPQSVTIFGESAGGVSVSAQVLSPLSKGLFHKAIAES 257

  Fly   254 GSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEV-PILEFLRNVNA---EKLIG------HDFISP 308
            |..:.|            .|.||     ..||: |:|..:.|:::   ..|:|      .|.|..
 Frog   258 GVAILP------------GLMTS-----KTEEILPLLSVVANISSCSVSDLVGCLKKKTEDEIIA 305

  Fly   309 RDRCFGFLNPFAPVVGGL-VAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELL 372
            ......|| .|..||.|: :..|.::::....|..||.|:|              ::|
 Frog   306 ITAAMRFL-VFPAVVDGVFLPKPAEEILAAKESNPVPFLIG--------------INN------- 348

  Fly   373 KHEPAMVLPHEL----YQSMSVEERN---------------TAADVLVKYHYGPRGITKSNITQI 418
             ||...:||..|    |:. .:|::|               :|...:::.::|.....|......
 Frog   349 -HEFGWILPLSLNITGYRE-GMEKKNIQATLGALPLLNTVSSAIPFIMEEYFGDTDDPKELRNNF 411

  Fly   419 LDLFSYKLFWHGIHRVVLSRLSHAQ------APTYLYRFDF------DSPKLNLMRNQLCGDDIK 471
            |||....:|       |:..|..|:      .|.|.|.|..      ||.           ||..
 Frog   412 LDLVGDIIF-------VIPALRTAKYHRDSGFPVYFYEFQHRPSMYADSK-----------DDFV 458

  Fly   472 RGVCHADDL-----------GYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGP 525
            : ..|.|:|           |.:|......::.:.|.   ||.:   ....|||.||||  ..|.
 Frog   459 K-ADHGDELYFVVGGPFLKSGILFKSNGTEEEKILSK---TIMK---YWANFARNGDPN--GLGL 514

  Fly   526 DPWMPVSTKSPFKALNIGQQVECVTQVEKDG-LKVW 560
            ..|........:..:|:.|:   .:|..|.| ||.|
 Frog   515 AEWPKYDEDEDYLEINLTQK---SSQRLKGGRLKFW 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	165/562 (29%)
ces2.2	XP_004913616.1	COesterase	36..547	CDD:395084	172/585 (29%)