Protein Alignment alpha-Est6 and ache

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 181/621 - (29%)
• Similarity: 250/621 - (40%)
• Gaps: 142/621 - (22%)

  Fly    15 CFRFLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKA 79
            |...|.|...|..    .||.|   ..:|....|.|:|.| ..:......:|.|||||:||:.|.
 Frog    10 CLCTLSLLLVPAL----TQSDG---GLLVSTRSGKVRGLR-QPVLSTHVSAFLGIPFAEPPVDKM 66

  Fly    80 RFVASQLADPWNSELDA------------------------RQERPIPLQMDRRSGKVVGSEDCL 120
            ||..|:...||....||                        ...||:             |||||
 Frog    67 RFRRSEPKKPWTDVWDATAYPNACYQYFDTLYPGFPGMEMWNPNRPM-------------SEDCL 118

  Fly   121 YLNVYTKHFNESEPPLP----VMVYIYGGAFRTGGAVKSKYGPDYLM-SRDVVYVLFNYRLCSLG 180
            |||::..|      |.|    |||:||||.|.:|.:....|...||. :.:|:.|..|||:.:.|
 Frog   119 YLNIWVPH------PRPSNATVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFG 177

  Fly   181 FLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGL 245
            ||::..|.:|.|||.||.||.||||||..:|..|.|||:.:|:|||||||.||...:..|.:..|
 Frog   178 FLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVGMHVLSPGSHHL 242

  Fly   246 FHKAIMMSGSMLSPWVNAPDSD--------GIF--CRLATSAGYEGPAEEVPILEFLRNVNAEKL 300
            |.||.:.|||..:||......:        |.|  ||:         ..:..:|..||....::|
 Frog   243 FSKAALQSGSPNTPWATITPQEARRRTELLGKFLDCRM---------GNDTELLNCLRVKQPQEL 298

  Fly   301 IGHDF-ISPRDRCFGFLNPFAPVV-GGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQL 363
            |.|:| :.|....|.|  .|.||. ......|.:.||........||::|....||
 Frog   299 IDHEFSVLPAPSVFRF--AFVPVPDADFFPEPPEILMNMGRFKPCPLIMGVNQNEG--------- 352

  Fly   364 DNGYML-----ELLKHEPAMVLPHELY--QSMSVEERNTAA--DVLVKY------HYGPRGITKS 413
              .|.|     ...|:..:::...|..  ..|||.:.|..|  .|:::|      |.|.:  .:.
 Frog   353 --SYFLLYGAPGFSKNNESLITREEFLGGVKMSVPQANDIALEAVVMQYTDWADEHAGVK--NRE 413

  Fly   414 NITQILDLFSYKLFWHGIHRVVLSRLSH-----AQAPTYLYRFDFDSPKLNLMRNQLCGDDIKRG 473
            .:.|::          |.|.|:.. |::     |:....:|.:.||....||...|.      .|
 Frog   414 AMDQLV----------GDHNVICP-LTYFAGKVAETGNRVYTYFFDHRASNLAWPQW------MG 461

  Fly   474 VCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGPDPWMPVSTKSP-- 536
            |.|..::.::|.....|.......|....:||:.....||||||||.......|..|:.|.|.
 Frog   462 VPHGYEIEFVFGLPLDANLNYTPQEEALSRRMMRYWANFARTGDPNEGNDAHQPRWPLYTASEQR 526

  Fly   537 FKALNIGQQVECVTQVEKDGLKV-----WNRLYSDL 567
            :.|||.....|.      .|::|     |||....|
 Frog   527 YMALNNKPYQEL------QGIRVQTCMFWNRFLPKL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	163/557 (29%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	170/584 (29%)
		AChE_tetra	564..597	CDD:430146