Protein Alignment alpha-Est6 and nlgn3

DIOPT Version :10

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 155/608 - (25%)
• Similarity: 242/608 - (39%)
• Gaps: 182/608 - (29%)

  Fly    40 SKVVKLSVGSVKGRRL---SGIYG--DEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQE 99
            |:.|....|.::|.|:   |.|.|  |::.   |:|:|.||:|:.||:..:....|:...:|...
 Frog    35 SQTVNTHYGKLRGTRVPLPSEILGPVDQYL---GVPYAAPPVGEKRFLPPEPPPSWSGIRNATHF 96

  Fly   100 RPI--------------PLQMDRRSGKVVG-----SEDCLYLNVY-------------------- 125
            .|:              |:........|.|     ||||||||:|
 Frog    97 SPVCPQNIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISKECVRKPNKK 161

  Fly   126 ----------------TKHFNESEPPL------PVMVYIYGGAFRTG------GAVKSKYGPDYL 162
                            :.:..:.|..:      ||||||:||::..|      |:|.:.||
 Frog   162 ICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIHGGSYMEGSGNMIDGSVLASYG---- 222

  Fly   163 MSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGES 227
               :||.:..|||:..|||||  :|.....||.||.||:.||:|||:::..|.|||..||:||..
 Frog   223 ---NVVVITLNYRVGVLGFLS--TGDQAAKGNYGLLDQIQALRWVSENVAFFGGDPHRITVFGSG 282

  Fly   228 AGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPW-VNAPD-------SDGIFCRLATSAGYEGPAE 284
            .||:.|..:.....::|||.:||:.|||.||.| ||...       ::.:.|.:         .:
 Frog   283 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNV---------LD 338

  Fly   285 EVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVV-GGLVAAPFQQLMKEAWSCEVPLLLG 348
            .|.:::.||..:|::|:..|....|     :...|.||: |.::....:.||::.......::||
 Frog   339 TVDMVDCLRQKSAKELVEQDIQPAR-----YHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 398

  Fly   349 GTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYG-PRGITK 412
            ....|||.:     ::|             |:..|  ..:|..:.:.:....|...|| |.|  |
 Frog   399 VNQGEGLKF-----VEN-------------VVDAE--DGVSGSDFDYSVSNFVDNLYGYPEG--K 441

  Fly   413 SNITQILDLFSY-----------------KLF----WHGIHRVVLSRLSHAQ--APTYLYRFDFD 454
            ..:.:.:. |.|                 .||    |  :...|::...||:  :|||.|.|
 Frog   442 DTLRETIK-FMYTDWADRDNPETRRKTLVALFTDHQW--VEPSVVTADLHARYGSPTYFYAF--- 500

  Fly   455 SPKLNLMRNQLCGDDIK---RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGIL-----TT 511
                    ...|...:|   ....|.|::.|:|.........|....|.....|:..:     |.
 Frog   501 --------YHHCQSLMKPAWADAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTN 557

  Fly   512 FARTGDPNCPETGPDPWMPVSTK 534
            ||:|||||.|       :|..||
 Frog   558 FAKTGDPNKP-------VPQDTK 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	39..536	CDD:395084	155/608 (25%)
nlgn3	XP_012823589.1	COesterase	35..618	CDD:395084	155/608 (25%)