Protein Alignment alpha-Est6 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 634
• Identity: 171/634 - (26%)
• Similarity: 255/634 - (40%)
• Gaps: 152/634 - (23%)

  Fly    31 SCQSAGDADSK--VVKLSVGSVKG--RRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWN 91
            |||.|....:|  :|....|.::|  :.|:.........:.|:|:|.||:|:.||...:....|.
Zfish    40 SCQRADLTTAKHPMVTTGYGKLRGVRKELNNEILGPVEQYLGVPYATPPVGERRFQPPEAPGSWQ 104

  Fly    92 SELDARQERPIPLQ------------------MDRRSGKVVG-SEDCLYLNVY--------TKHF 129
            ...:|.|..|:..|                  :|..:..|.. ||||||||||        ||..
Zfish   105 EIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYLNVYVPTEDGPLTKKH 169

  Fly   130 NES------------EPPLPVMVYIYGGAFRTG------GAVKSKYGPDYLMSRDVVYVLFNYRL 176
            :||            ....|||::|:||:|..|      .:|.:.||       :|:.|..||||
Zfish   170 DESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFDASVLAAYG-------NVIVVTMNYRL 227

  Fly   177 CSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQ 241
            ..|||||  ||.....||.||.||:.||:|::::|.:|.|||:.||:||..|||:.|:.::....
Zfish   228 GVLGFLS--SGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHH 290

  Fly   242 AKGLFHKAIMMSGSMLSPW-VNAPDSDGIFCR-LATSAG--YEGPAEEVPILEFLRNVNAEKLIG 302
            ::|||.:||..|||.:|.| ||....  ::.: ||...|  |...|:   :::.||..:..:|:.
Zfish   291 SEGLFQRAIAQSGSAISSWSVNYRPL--MYTKILAKKVGCSYSDTAD---LVDCLRRKSYRELVD 350

  Fly   303 HDFISPRDRCFGFLNPFAPVV-GGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNG 366
            .|....|     :...|.||| |.:|....:.||::.......:|||....|||.:..    ||
Zfish   351 QDVQPAR-----YHIAFGPVVDGDVVPDDPEILMQQGEFLNYDILLGVNQGEGLKFVD----DN- 405

  Fly   367 YMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYG-PRG--ITKSNI------------- 415
                            |..:.:|....:......|...|| |.|  |.:..|
Zfish   406 ----------------EGEEGISAASFDYTISNFVDNLYGYPEGKDILRETIKFMYTDWADRDNG 454

  Fly   416 ----TQILDLFSYKLFWHGIHRVVLSRLSHA--QAPTYLYRFDFDSPKLNLMRNQLCGDDIK--- 471
                ..:|.||:... |  :...|.:...||  |:|.|.|.|           :..|..:.:
Zfish   455 DMRRKTLLALFTDHQ-W--VAPAVATAKLHAEFQSPVYFYTF-----------HHHCQTEARPEW 505

  Fly   472 RGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGIL-----TTFARTGDPNCP--------ET 523
            ....|.|::.|:|.........|....|.....|:..:     |.||:|||||.|        .|
Zfish   506 ADAAHGDEIPYVFGVPMVGATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHT 570

  Fly   524 GPDP-----WMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLYSDL 567
            .|:.     |...|:|.. :.|:||.:.........:.:..|..|...|
Zfish   571 KPNRFEEVIWTKFSSKDK-QYLHIGLKPRIRDNYRANKVAFWLELVPHL 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	161/595 (27%)
		Aes	<133..325	CDD:223730	72/202 (36%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	164/618 (27%)
		Aes	<181..>279	CDD:223730	43/106 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740