Protein Alignment alpha-Est7 and Ces1h

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 606
• Identity: 177/606 - (29%)
• Similarity: 259/606 - (42%)
• Gaps: 172/606 - (28%)

  Fly    34 VADTEYGQVRGIKRLSL--YDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRD-------CS 89
            |.:|.:|:|.| |.:||  :..|...|.|:|:|:||:|.|||..||.|.||..|::       ||
Mouse    25 VVNTTHGKVLG-KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCS 88

  Fly    90 QPKDKAVQVQFVFD---------KVEGSEDCLYLNVYT--NNVKPDKARPVMVWIHGGGFIIGEA 143
            |   .||..|.|.|         ::..|||||||||||  :.:|.....||||||||||.::|.|
Mouse    89 Q---DAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGA 150

  Fly   144 NREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGD 208
            : .:.|......|:||:|||||||...||.|  :.:.:..||.|..||:.||.||::|.|:||||
Mouse   151 S-AYDGRTLSAHENVVVVTIQYRLAIWGFFS--TGDEHSRGNWGHLDQLAALHWIQDNIANFGGD 212

  Fly   209 PNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYK-- 271
            |..:|:||:||||.|...::|:...:.||||.|.|||.......:..|.:....:||...|.|
Mouse   213 PGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTT 277

  Fly   272 ---------GEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMN-KIMFAFGPSLEPFSTPECVI 326
                     .:..::::||.:|.:          |:..|:.:.| |..:.|.|::    ....|:
Mouse   278 TSAVIVHCLRQKTEEELLEIMQKM----------NLFKLDAQENTKKNYPFLPTV----LDGVVL 328

  Fly   327 SKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVP--------EVKL--------------------- 362
            .|.|:.::.....|::|..:|....|....:|        :|||
Mouse   329 PKAPEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPED 393

  Fly   363 -MPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQ-IRDVHRTGSESTPDNYMDLCSIYYFVFP 425
             :|..:::...||         .:|.:.::  |..| |.||                   .|..|
Mouse   394 GIPVAIEKYSKGT---------DDPIQNRV--WLLQLIGDV-------------------MFGIP 428

  Fly   426 ALRVVHSRHAYAAGAPVYFYRY----DFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLAR 486
            :  |:.||....||||.|.|.:    .|.||  :.|       :.|.| .|.|::...|.:.:.|
Mouse   429 S--VIVSRGHRDAGAPTYMYEFQSRPSFSSE--LKP-------KTVTG-DHGDEVYSVFGAPILR 481

  Fly   487 RLPKESREYRNIER-TVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFID 550
            .  ..|.|..|:.: .:..|..||..|||     ||.                           .
Mouse   482 E--GSSEEEINLSKMMMKFWANFARNGNP-----NGQ---------------------------G 512

  Fly   551 LPEWPKLKVWESLYDDNKDLL 571
            ||.||:       |:..|..|
Mouse   513 LPHWPE-------YNQKKGYL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	166/547 (30%)
		Aes	<116..>221	CDD:223730	51/106 (48%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	177/606 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832587
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640