Protein Alignment alpha-Est7 and Ces2j

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_038953911.1
• Gene: Ces2j / 685645
• RGDID: 1591368
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 185/604 - (30%)
• Similarity: 272/604 - (45%)
• Gaps: 124/604 - (20%)

  Fly     8 VERLRWRLKTIE----HKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDVP-----YFSFEGIPY 63
            :.|.|.|.|.|.    |.....:...:.:.:.:|..|||||    |...|.     ..:|.|||:
  Rat    23 LRRERERKKGIPDSNLHSFLTEQGQDSASPIRNTHTGQVRG----SFVHVKDTKSGIHTFLGIPF 83

  Fly    64 AQPPVGELRFKAPQRPIPWERVRDC-SQPKDKAVQVQFVFDKVEG-----------SEDCLYLNV 116
            |:||||.|||..|:.|.||..|||. |||   |:.:|.....:||           ||||||||:
  Rat    84 AKPPVGPLRFAPPEDPEPWSGVRDATSQP---AMCLQTAMMNLEGMKETELTKLPMSEDCLYLNI 145

  Fly   117 YT-NNVKPDKARPVMVWIHGGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPEL 180
            |. .:...|...||||||||||.:.|.|:.. ........|::|:|:||||||.|||.|  :.:.
  Rat   146 YVPAHAHEDSNLPVMVWIHGGGLVGGSASMN-DASTLAATEEIVIVSIQYRLGVLGFFS--TGDQ 207

  Fly   181 NVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSG 245
            :..||.|..||:.||:|::.|.|.|||:.:.:|:||.||||.|....:::..::|||||.|:|||
  Rat   208 HARGNWGYLDQMAALRWVQQNIAYFGGNRDSVTIFGVSAGGTSVSSHVVSPMSKGLFHRAIMQSG 272

  Fly   246 SAICPWAYNGDITHNPYR-IAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIM 309
            .|:.|...: |.:...|: :|.|.|.:..|::    ..::.::||.    ::.:|.:.:....|
  Rat   273 VALLPGLIS-DTSEVVYKTVANLSGCEASDSE----ALIRCLRAKS----KQEILAINQVFKMI- 327

  Fly   310 FAFGPSLEPFSTPECVISKPPKEMMKTAWSNSIPMFIG-NTSYEGLLW-VPEV------------ 360
                    |.......:.|.|:|::.:...:.:|..|| ||...|  | ||.:
  Rat   328 --------PGVVDGKFLPKHPQELLASKDFHPVPSIIGVNTDECG--WGVPTILGLYHIINNITR 382

  Fly   361 KLMPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFP 425
            :.:|..| ::.|....:|.|.:..     .::.:.....|     :|:....:.::...:.||.|
  Rat   383 ETLPAAL-KIAAAQMMLPPECIDL-----IMEEYMGDTED-----AETLQAQFKEMLGDFIFVIP 436

  Fly   426 ALRVVHSRHAYAAGAPVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSS-------- 482
            ||:|.|.:.:.   ||||||.:   ...|.|   |.::........|.||..:.|.|
  Rat   437 ALQVAHFQRSQ---APVYFYEF---QHLLSF---IKQVRPFYPKADHGDDTVFVFGSYFWGMTFD 492

  Fly   483 ------LLARRLPKESREYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLN 541
                  ||.||:.|             .|..||.||||     ||.| |...||...||....||
  Rat   493 LTEEEELLKRRVMK-------------YWANFARTGNP-----NGED-LPHWPVLDHDEQYLQLN 538

  Fly   542 ----ISDDLKFIDLPEWPK 556
                :...||...|..|.|
  Rat   539 SQPAVGRALKARRLQFWTK 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	162/526 (31%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	177/573 (31%)