Protein Alignment alpha-Est7 and Ces1a

DIOPT Version :10

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 174/586 - (29%)
• Similarity: 251/586 - (42%)
• Gaps: 133/586 - (22%)

  Fly    34 VADTEYGQVRGIKRLSL--YDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRD-------CS 89
            |.||..|:|.| |.:||  :..|...|.|:|:|:||:|.|||..||....|..|::       ||
  Rat    25 VVDTLQGKVLG-KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCS 88

  Fly    90 QPKDKAVQVQFVFDK------VEGSEDCLYLNVYTNNVKPDKAR-PVMVWIHGGGFIIGEANREW 147
            |.......:..||..      :|.||||||||:|:......|.| |||||:||||.:.|.|: .:
  Rat    89 QITGVGPVLSEVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGAS-TF 152

  Fly   148 YGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCI 212
            .|......|.||:|.||||||..||:|  :.:.:..||.|..|||.||:|::||..:||||||.:
  Rat   153 DGLALSTHEKVVVVVIQYRLGIWGFLS--TGDEHSRGNWGHFDQVAALQWVQNNIVNFGGDPNSV 215

  Fly   213 TVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGEDNDK 277
            |:|||||||.|...::|:..|:.||||.|.:||.|:.|..:..:......::|...|. ......
  Rat   216 TLFGESAGGESVSVLVLSPLTKNLFHRAISESGVALTPCLFRENTRLAAEQVAIATGC-AATTSA 279

  Fly   278 DVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAF---GPSLE--PFST---PECVISKPPKEMM 334
            |::..|:.       :.||.:|....:|.  .||.   |...|  ||.|   ...::.|.|:|::
  Rat   280 DIVRCLRE-------KTEEELLATTLKMK--FFALDLHGDPRESYPFLTTVIDGVLLPKAPEEIL 335

  Fly   335 KTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGT---------PF--IPKEL--LATE- 385
            .....|::|..:|....|...::|.:...|....:||..|         |.  |.|||  :|||
  Rat   336 SEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLLWKSYPLTNISKELTPVATEK 400

  Fly   386 -------PSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVY 443
                   |.|:|                    |.::|:.....|..|:  |:.:|:...|.|..|
  Rat   401 YLGGSDCPDKKK--------------------DLFLDMMGDVLFAVPS--VIVARYHRDARATTY 443

  Fly   444 FYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKE--SREYRNIE-RTVGIW 505
            .|.:.:      .|..:..:........|.|::    .|:......||  |.|..|:. ..:..|
  Rat   444 VYEFKY------HPSFVSDMRPKTVIADHGDEV----YSVWGTPFLKEGASEEEINLSTMMMKFW 498

  Fly   506 TQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLKVWESLYDDNKDL 570
            ..||..|||..|                                .||.||:       ||:.:..
  Rat   499 GNFARNGNPNGE--------------------------------GLPHWPE-------YDEKESY 524

  Fly   571 L 571
            |
  Rat   525 L 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	164/527 (31%)
Ces1a	NP_001177304.1	COesterase	22..545	CDD:395084	174/586 (30%)