Protein Alignment alpha-Est7 and Ces5a

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 600
• Identity: 174/600 - (28%)
• Similarity: 254/600 - (42%)
• Gaps: 180/600 - (30%)

  Fly    37 TEYGQVRG-----IKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKAV 96
            |:.|.|:|     :.||.    |...|.|||:|.||:|.|||..||.||||:.:|:.:...:...
Mouse    39 TKLGWVQGKQATVLGRLE----PVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCF 99

  Fly    97 Q-VQFVFD-----KVE-----GSEDCLYLNVY----TNNVKPDKARPVMVWIHGGGFIIGEANRE 146
            | ::::|.     ||.     .||||||||:|    .||   ..:.||||||.||||..|.|: .
Mouse   100 QNLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANN---GSSLPVMVWIPGGGFETGSAS-I 160

  Fly   147 WYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNC 211
            :.|....:.|||::||||||||..||.:.::.  :.|||....||:.||.|::.|...|||:|:.
Mouse   161 FDGSALAVYEDVLVVTIQYRLGIFGFFTTQNQ--HAPGNWAFWDQLAALLWVRENIKYFGGNPDS 223

  Fly   212 ITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICP--WAYNGDITHNPYRIAKLVGYKGED 274
            :|:||.|||..|...::|:..:..||||.|:|||.||.|  .:.:.|:.|:...:|.:......|
Mouse   224 VTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVVANVCDCNVSD 288

  Fly   275 N--------DKDVLEFLQ-NVKAKDLIRV-------EENVLTLEERMNKIMFAFGPSLEPFSTPE 323
            :        :|..||.:. :.|||...||       ||.:..|.::..||:    ||:...:..|
Mouse   289 SKALLKCLREKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIV----PSIIGVNNQE 349

  Fly   324 CVISKP----PKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLAT 384
            |....|    |:.::.:..|.::      |....||.:|...|.            .:.||....
Mouse   350 CGYILPVRDTPEILLGSNESTAL------TLIHTLLHIPTQHLY------------IVTKEYFHG 396

  Fly   385 EPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYD- 448
            :.|       ...||           |..:||....:||.|.|  |.:|:...:|.|||||.:.
Mouse   397 KHS-------PTDIR-----------DTLLDLFGDVFFVVPGL--VTARYHRDSGGPVYFYEFQH 441

  Fly   449 ----FDSEELIFPYRIMRLGRGVKGVSHADDLSYQF------------------SSLLARRLPKE 491
                |.:....|          || ..|.|::.:.|                  ..||:|::.|
Mouse   442 RPHCFQNSRPAF----------VK-ADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMK- 494

  Fly   492 SREYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPK 556
                        .|..||.:|:|     ||                           .|||.||
Mouse   495 ------------YWANFARSGDP-----NG---------------------------ADLPPWP- 514

  Fly   557 LKVWESLYDDNKDLL 571
                  :||:|:..|
Mouse   515 ------VYDENEQYL 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	162/541 (30%)
		Aes	<116..>221	CDD:223730	47/108 (44%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	173/599 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740