Protein Alignment alpha-Est7 and nlgn4xa

DIOPT Version :9

• Sequence 1: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 658
• Identity: 172/658 - (26%)
• Similarity: 267/658 - (40%)
• Gaps: 175/658 - (26%)

  Fly     8 VERLR---WRLKTIEHKVQQYRQST--------------NETVVADTEYGQVRGIKRLSLYDV-- 53
            :.|||   |...|:.|.:...|..|              .:..:..|.||::||:|.....::
Zfish     1 MSRLRGTPWIPLTMVHPLATLRLFTWIVLAAAWLAITWAQQHPIVTTNYGKLRGLKTPLPNEILG 65

  Fly    54 PYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQ--PKDKAVQVQFVFDKV----------- 105
            |...:.|||||.||.||.||:.|:.|:.|..:|:.:|  |    |..||:.|:.
Zfish    66 PVEQYLGIPYALPPTGERRFQPPEPPMSWPGIRNATQFAP----VCPQFLEDRFLLNDMLPVWFT 126

  Fly   106 -----------EGSEDCLYLNVY--TNNVKPDKA--------------------RPVMVWIHGGG 137
                       :.||||||||:|  |.:|..:|.                    |||||:||||.
Zfish   127 ANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNEGGENKDIHDENGLRPVMVYIHGGS 191

  Fly   138 FIIGEANR------EWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALK 196
            ::.|..|.      ..||       :|::||:.||||.|||:|  :.:....||.||.||:.||:
Zfish   192 YMEGTGNMIDGSILASYG-------NVIVVTLNYRLGVLGFLS--TGDQAAKGNYGLLDQIQALR 247

  Fly   197 WIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNP 261
            |||.|..:|.|||..:|:||..||.:....:.|:..::.||.:.|:|||:|:..||.|    :.|
Zfish   248 WIKENIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVN----YQP 308

  Fly   262 YRIAKLVGYKGEDN---DKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPE 323
            .:..:::..|...|   ..|::|.|||...|:||   |..:|    ..|...||||.::     .
Zfish   309 AKYTRILAEKVGCNMLDSIDLVECLQNKNYKELI---EQYIT----QAKYHIAFGPVID-----G 361

  Fly   324 CVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLD---AGTPFIP------- 378
            .||...|:.:|:.....:..:.:|....||..:|..:......:...|   |.:.|:.
Zfish   362 DVIPDDPQILMEQGEFLNYDIMLGVNQGEGFKFVDGIVDSEDGVSANDFDFAVSDFVDHLYGYPE 426

  Fly   379 -KELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRV--VHSRHAYAAGA 440
             |:.| .|..|.....|:      .:...|:.....:.|.:.:.:|.||:..  :|:::    |:
Zfish   427 GKDTL-RETIKFMYTDWA------DKENPETRRKTLVALFTDHQWVAPAVATADLHAQY----GS 480

  Fly   441 PVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQF-------SSLLARRLPKESREYRNI 498
            |.|||.:....:..:.|        .....:|.|::.|.|       :.|......|.......:
Zfish   481 PTYFYAFYHHCQSEMKP--------SWSDSAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAV 537

  Fly   499 ERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFI-------DLPEWPK 556
            ..|  .||.||.||:|...                        :..|.|||       :...|.|
Zfish   538 VMT--YWTNFAKTGDPNQP------------------------VPQDTKFIHTKPNRFEEVAWSK 576

  Fly   557 LKVWESLY 564
            ....:.||
Zfish   577 YNPKDQLY 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est7	NP_524261.1	COesterase	27..514	CDD:278561	156/577 (27%)
		Aes	<116..>221	CDD:223730	48/132 (36%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:306613	164/616 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740